Science Data Systems provide the software and hardware infrastructure that bridge the gap between raw data and scientific discovery, encompassing key components such as data ingestion,  stewardship, product generation, dissemination, and visualizations. Despite their importance, these systems are often an overlooked and underfunded component of the scientific process, with their development remaining fragmented across various scientific domains. This session aims to foster collaboration across these domains by highlighting novel architectures, tools for science data processing, projects with opportunities for joint development, and lessons learned from designing, implementing, testing, operating, and maintaining science data systems. We welcome contributions from research scientists, software developers, scientific programmers, system engineers, project managers, data stewards, and all who are passionate about enhancing Science Data Systems. Whether you’ve developed an open-source tool, designed such a system under mission constraints, or have lessons to share from operational experiences, we want to hear from you!