As the U.S. federal government attempts to weaken and repeal environmental regulations, states such as Colorado, California, and New Mexico have implemented or are developing regulations for the oil and gas industry that aim to reduce natural gas waste and emissions of methane and volatile organic compounds. In addition, Canada and Mexico are implementing O&G methane rules, and several transnational O&G companies have announced targets to reduce emissions. This session will focus on science-based policies to reduce oil and gas emissions. Experts from groups including industry, government, and academia will highlight emerging policy and technological approaches to address emissions from oil and gas development. We welcome studies that use empirical data and/or modeling to evaluate the efficacy of regulations and voluntary initiatives. We also are interested in case studies of effective collaboration across stakeholder groups in advancing science-driven policy.