GH006-0001
Estimating Acute Effects of Ambient Ozone on Cause-Specific Mortality in China

Monday, 14 December 2020
Poster
Chen Chen1, Tiantian Li1, Xiaoming Shi2 and China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, (1)National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China, (2)National Institute of Environmental Health, Chinese Center for Disease Control and Prevention,, Beijing, China
Abstract:
Background: Given the rising health threat that ambient ground-level ozone (O3) pollution poses to human health due to its continuously increasing levels in China, estimating the acute effects of O3 pollution on health has become an important issue for public health and air pollution mitigation decision-making.

Methods: Using quasi-Poisson generalized additive models and random effects meta-analysis, we estimated the acute effects of O3 pollution on mortality from 2013 to 2018 in 130 counties in China. We included non-accidental mortality and 14 causes of cardio-cerebrovascular and respiratory mortality. Acute effects and their seasonal patterns were estimated as the percent increase associated with a per 10-μg/m3 change in maximum daily average 8-hour O3 concentrations (MDA8) in selected endpoints.

Results: The average MDA8 O3 nationwide was 90.4 ± 51.5 μg/m3, varying from 109.1-μg/m3 in warm seasons to 76.6-μg/m3 in cold seasons. Positive but non-significant associations were observed for O3 pollution in the whole study period. Per 10-μg/m3 increase in same day O3 pollution of warm seasons were associated with a 0.16% (95% CI: 0.08, 0.25%), 0.17% (95% CI: 0.05, 0.29%) and 0.12% (95% CI: -0.10, 0.33%) increase in non-accidental, cardio-cerebrovascular and respiratory mortality, respectively. Acute ischemic heart disease, acute myocardial infarction, and ischemic stroke were greatly affected. These acute effects on cardio-cerebrovascular deaths mostly peaked at lag 0 or lag 1-day exposure, while effects on respiratory deaths peaked at lag 3-day exposure.

Conclusions: Our findings add evidence that O3 pollution are more harmful for public health in warm seasons, especially diseases with rapid onset and fatal damage such as acute ischemic heart disease, acute myocardial infarction, and ischemic stroke. Our findings also suggest that O3-related acute effects on population mortality would be underestimated if seasonal patterns were ignored.

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