The Ocean Biomolecular Observing Network (OBON) is a global initiative designed to revolutionize ocean monitoring using biomolecular science, including environmental DNA (eDNA). Endorsed by the UN Ocean Decade, OBON leverages scientific advancements to enhance sustainability by providing real-time, large-scale monitoring of marine life and ecosystems. OBON has established a global biomolecular network that collects and analyzes eDNA and other biomarkers from coastal to open waters, with the aim to address critical issues such as pollution, biodiversity loss, and climate change. OBON is also developing capacity globally, to advance observations and analyses while ensuring equitable access to ocean knowledge and resources, and enhancing the use and interpretation of biomolecular data through Findable, Accessible, Interoperable and Reusable (FAIR) data practices and model integration, and the creation of ocean knowledge. This work will empower researchers, policymakers, and communities to manage and conserve ocean ecosystems more effectively. With its capacity to scale globally, OBON represents a vital tool in shaping sustainable ocean stewardship and advancing a comprehensive vision for ocean health in the coming decades. This session invites contributions that highlight advances in biomolecular methodologies and technologies, progress towards obtaining quantitative data from eDNA (or other biomolecules), and/or in the development of reference libraries.

• Coastal and Estuarine Biology and Biogeochemistry -
• Marine Ecology and Biodiversity -
• Ocean Technologies and Observatories -