Preliminary Program subject to change
03014 Agglomeration, Granulation and Particle Formation Processes
OverviewWe plan a session about all aspects of particles size increase i.e., formation of larger granules from fine particles with or without the use of a binder. This will cover wet-and melt-granulation, fluid bed granulation and coating and compaction under pressure. Papers are requested on both theoretical, computer modeling and experimental research performed on the above systems.
Primary SponsorParticle Technology Forum (03)

Chair

Paul Mort
Procter & Gamble Company
Ivorydale Technical Center
Cincinnati, OH 45217
Phone Number: 513-627-8876
Email: mort.pr@pg.com

CoChair

Rebecca L. Carrier
Assistant Professor
Department of Chemical Engineering
Northeastern University
Pharmaceutical R&D
457 Snell Engineering Center
Boston, MA 02115-5000
Phone Number: 617-373-7126
Email: rebecca@coe.neu.edu
Welcoming Remarks
Multidimensional Modeling of Granulation
Andreas Braumann1, Mike Goodson1, Markus Kraft1 and Paul Mort2, (1)Department of Chemical Engineering, University of Cambridge, Pembroke Street, Cambridge, CB2 3RA, United Kingdom, (2)Procter & Gamble Company, Ivorydale Technical Center, Cincinnati, OH 45217
Micromechanical Properties of Model Intragranular Bridges of Pharmaceutical Excipients
Farber Leon1, James N. Michaels1 and Gabriel I. Tardos2, (1)Pharmaceutical Materials Laboratory, Merck & Co Inc., PO Box 4, WP78A-31, West Point, PA 19486, (2)Department of Chemical Engineering, The City College of the City University of New York, 140th Street & Convent Ave, New York, NY 10031
Determination of the Coalescence Probability of Wet Granules by Mesoscale Modeling
Frantisek Stepanek1, Pavol Rajniak2, Christopher Mancinelli2 and Rey Chern2, (1)Imperial College London, South Kensington Campus, London, SW7 2AZ, UK, (2)Research Laboratories, Merck & Co., Inc., WP78-110, PO Box 4, West Point, PA 19486-0004
A Micro-Mechanistic Investigation of the Effects of Binder Surface Tension in Pharmaceutical Granulation
Cristina Jimenez1, Stefaan J Simons1, Rob Ward2 and Shaun Fitzpatrick2, (1)Chemical Engineering, University College London, Torrington Place, London, WC1E 7JE, United Kingdom, (2)ERP Phase 2a Site Champion, Devlab, Merck Sharp & Dohme, Hertford Road, Hoddesdon, Herts, EN11 9BU, United Kingdom
Adhesion Force and Wetting Behaviour of Las Acid Bridges: A Comparison of Different Neutralisation States in Relation to Detergent Granulation
Sarah Germaná1, Stefaan J.R. Simons1 and Judith Bonsall2, (1)Department of Chemical Engineering, University College London, Torrington Place, London, WC1E 7JE, United Kingdom, (2)Process Science, Unilever R&D Port Sunlight, Quarry Road East, Bebington, CH63 3JW, United Kingdom
Wet Granule Breakage in High Shear Mixer Granulation
James D. Litster1, Rachel Smith2 and Neil Page1, (1)School of Engineering, The University of Queensland, St Lucia, 4060, Australia, (2)Division of Chemical Engineering, The University of Queensland, St Lucia, 4060, Australia
Discrete Element Method Application for Verification of Kinetic Theory of Granular Flow in a High Shear Mixer
Justin A. Gantt, Chemical Engineering, University of South Carolina, Dept. of Chemical Engineering, Swearingen Engineering Center, 301 Main St., Columbia, SC 29208 and Edward P. Gatzke, University of South Carolina, Dept. of Chemical Engineering, Swearingen Engineering Center, 301 Main St., Columbia, SC 29208
Use of Lasentec Fbrm in-Process Particle Sizing Pat Technique to Study Top- and Bottom-Spray Fluid Bed Granulation Processes
Mario Hubert1, Benjamin Smith1, Eric Dycus2, Andrew Birkmire3 and Kim T. Walter3, (1)Particle Systems Characterization - Process Analytical Technology, METTLER TOLEDO, Redmond, WA 98052, (2)Particle Systems Characterization, METTLER TOLEDO, Redmond, WA 98052, (3)Niro Pharma Systems, Columbia, MD

Particle Technology Forum