Preliminary Program subject to change
08B04 Biomaterials for Gene Therapy and Drug Delivery
OverviewThis session will cover the design and utilization of biomaterials for gene therapy and drug delivery applications with particular focus on how biomaterial properties (e.g. mechanical properties, chemical composition, degradation kinetics, micro/nano-structure, etc.) match the specific gene therapy or drug delivery application. Possible topics include, but are not limited to, stimuli-sensitive or targeted delivery, enhancement of transfection efficiency with specific biomaterial properties, novel biomaterials for macromolecular delivery, and influence of biomaterials on intracellular trafficking or transport of drugs.
Primary SponsorBiomaterials (08b)

Chair

Lonnie D Shea
Assistant Professor
Northwestern University
2145 Sheridan Rd / E156
Evanston, IL 60208-3120
Phone Number: 847-491-7043
Fax Number: 847-491-3728
Email: l-shea@northwestern.edu

CoChair

Howard W. Matthew
Associate Professor
Wayne State University
Dept. Chemical Engineering
5050 Anthony Wayne Drive
Detroit, MI 48202
Phone Number: 313-577-5238
Fax Number: 313-577-3810
Email: hmatthew@wayne.edu
Functionalizable Polymer Precursors for Non-Viral Gene Delivery Vectors
Sharon Y. Wong, Biomedical Engineering, Cornell University, 120 Olin Hall, Ithaca, NY 14853 and David Putnam, Chemical and Biomolecular Engineering, Cornell University, 120 Olin Hall, Ithaca, NY 14853
Synthesis and in Vitro Characterization of a Triblock Copolymer Carrier for Sirna
Tatiana Segura, EPFL, IGBB, Bat. AAB-231, Lausanne, 1015, Switzerland and Jeffrey A. Hubbell, EPFL, IGBB, Bat. AA-B 039, Lausanne, CH-1015, Switzerland
An Anionic Polymer Enhances Cationic Lipid-Mediated Delivery of Antisense Oligonucleotides
Li Kim Lee, Charity L. Williams and Charles M. Roth, Department of Chemical & Biochemical Engineering, Rutgers University, 98 Brett Road, Piscataway, NJ 08854
Multilayered Polyelectrolyte Films for the Localized Delivery of DNA to Cells
Christopher M. Jewell, Jingtao Zhang, Nathaniel J. Fredin and David M. Lynn, Department of Chemical and Biological Engineering, University of Wisconsin - Madison, 1415 Engineering Drive, Madison, WI 53706
Patterned Substrate-Mediated Gene Delivery Using Microfluidics
Tiffany Houchin, Department of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Road, Tech E136, Evanston, IL 60208 and Lonnie D. Shea, Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Road, Tech E136, Evanston, IL 60208
Development and in Vitro Evaluation of a Peg-Insulin Conjugate Protein for the Treatment of Diabetes Mellitus
Anthony D. Tuesca, Dept. of Chemical and Biological Engineering, Drexel University, 3141 Chestnut St., Philadelphia, PA 19104 and Anthony M. Lowman, Drexel University, Department of Chemical Engineering, Philadelphia, PA 19104
Engineering Shape of Polymeric Microparticles for Drug Delivery
Julie Champion and Samir Mitragotri, Chemical Engineering, University of California Santa Barbara, Engineering II Rm 3229, Santa Barbara, CA 93106
Engineering Nanoscale Hydrogel Particles Entrapping Bovine Hemoglobin as Temperature and pH Sensitive Oxygen Carriers
Andre Palmer and Jaqunda Patton, University of Notre Dame, Department of Chemical Engineering, University of Notre Dame du Lac, Notre Dame, IN 46556

Materials Engineering and Sciences Division