Preliminary Program subject to change
15B01 Pharmaceutical Product/Process Development & Scale-up: Part 1
OverviewThis session welcomes submissions detailing studies of pharmaceutical unit operations used to produce final dosage forms. Studies at scales ranging from small-scale pilot plant through production are welcome. This session is continued as Pharmaceutical Product/Process Development & Scale-up: Part 2 (Session 15B00)
Primary SponsorPharmaceuticals (15b)

CoChair

Michael B. Mackaplow
Abbott Laboratories
Dept. 4P8, Bldg. A4
1401 Sheridan Road
North Chicago, IL 60064-6235

Phone Number: 847-938-0808
Fax Number: 847-785-2220
Email: michael.b.mackaplow@abbott.com

CoChair

John F. Peragine
Principal Technical Investigator
Bristol-Myers Squibb Company
1 Squibb Drive
Bldg. 137 rm 389
New Brunswick, NJ 08903
Phone Number: 732 227-5688
Fax Number: 732 227-3892
Email: john.peragine@bms.com
High Shear Wet Granulation: Scale-up Insights Derived from Granule Size and Porosity Measurements
Sunil V. Jain, Maryam Moaddeb, Luke A. Kline and Russell V. Plank, Pharmaceutical R&D, Merck & Co., WP 78-110, West Point, PA 19486
Use of a Novel Shear Cell to Study the Influence of Shear Intensity and Total Shear on the Properties of Pharmaceutical Blends
Amit Mehrotra, Abdul M. Faqih, Marcos Llusa and Fernando J. Muzzio, Rutgers University, Dept. of Chemical and Biochemical Engineering, 98 Brett Road, Piscataway, NJ 08854
Enhancing the Physical Stability of Tablets through Moisture Control across the Pharmaceutical Process
Luke Schenck1, Brian Sell1, Nick Birringer1, Michelle Kenning2 and Russell Plank1, (1)Pharmaceutical Development, Merck, WP78-110 PO Box 4, West Point, PA 19486, (2)Pharmacuetical Development, Merck, WP78-204 PO Box 4, West Point, PA 19486
Mixing Scale-up for Pharmaceutical and Biological Processes
David S. Dickey, MixTech, Inc., 454 Ramsgate Drive, Dayton, OH 45430-2097
Break
Biopharmaceutical Scale-up and Scale-down Using Fluid Mixing Analysis and Computational Fluid Dynamics (CFD)
Richard D. LaRoche, Fluent Inc., 10 Cavendish Ct., Lebanon, NH 03766
Redundant Filtration Sizing and Scale up in Sterile Filtration Applications
Pritipal S. Bhinder, Wenchang Ji, H. Gerald Sparks, Manpreet-Vick Wadhwa, Sugunakar Patro and Erwin Freund, Drug Product Process Development, Amgen Inc, Thousand Oaks, CA 91320
Challenges of Scaling up a Highly Hydrophobic Corticosteroid
Anayo M. Ukeje, Nasal Spray Product Development, Morton Grove Pharmaceuticals INC., 50 Lakeview Parkway,, Suite 127, Vernon Hills, IL 60061 and Chirag D. Chodankar, Research & Development, Morton Grove Pharmaceuticals, Inc., 50 Lakeview Parkway,, Suite 127, Vernon Hills, IL 60061

Food, Pharmaceutical & Bioengineering Division