Preliminary Program subject to change
15C01 Advances in Animal and Insect Cell Culture
OverviewWe invite papers focusing on cultivation and utilization of insect and mammalian cells. Studies may involve bioreactor design and optimization, cell line development, recombinant protein production, and other related issues. Papers are also sought that investigate the role of cultivation conditions on physiological responses, such as changes in apoptosis, oxidative stress, protein expression, and gene expression.
Primary SponsorBioengineering (15c)
Co-Sponsor(s)Research and New Technology Committee (18j)

Chair

Sigma Mostafa


Email: sigma_mostafa@lilly.com

CoChair

Michael Betenbaugh
Professor and Chair, Department of Chemical Engineering
Johns Hopkins University
3400 N. Charles Street
221 Maryland Hall
Baltimore, MD 21218
Phone Number: (410) 516-5461
Fax Number: (410) 516-5510
Email: beten@jhu.edu
Baculovirus as a Tool for Eucaryotic Protein Expression in Mammalian Cells
Ying-Wei Chiang, Kuei-Chun Wang, Jen-Te Lu, Chia-Wei Lai, Yao-Chi Chung and Yu-Chen Hu, Department of Chemical Engineering, National Tsing Hua University, 101, Sec. 2, Kuang Fu Rd., Hsinchu, Taiwan
Improved Oxygen Delivery to Hepatocytes Maintained within a Hollow Fiber Bioreactor Via Bovine Red Blood Cell Supplementation of Circulating Culturing Media
Andre Palmer, Jason Gordon and Jesse Sullivan, University of Notre Dame, Department of Chemical Engineering, University of Notre Dame du Lac, Notre Dame, IN 46556
Improving Culture of Islets of Langerhans: Removing Oxygen Limitations
Michael James Rappel1, Klearchos K. Papas2, Efstathios S. Avgoustiniatos2, Linda A. Tempelman3 and Clark K. Colton4, (1)Chemical Engineering, Massachusetts Institute of Technology, Bldg 66-457, 77 Massachusetts Ave, Cambridge, MA 02139, (2)Surgery, Diabetes Institute for Immunology and Transplantation, University of Minnesota, MMC 195, 420 Delaware Street SE, Minneapolis, MN 55455, (3)Giner, Inc, 89 Rumford Ave, Newton, MA 02466, (4)Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139
Improving Therapeutic Protein Quality in Gs-Ns0 Cell Lines Using Culture Supplements
Sigma S. Mostafa and Johnny Andraous, Eli Lilly & Company, 1223 W. Morris Street, Indianapolis, IN 46221
Intermission
Genome-Wide Analysis of the Transcriptional Response of Murine Hybridomas to Osmotic Shock
Susan Sharfstein and Duan Shen, Chemical and Biological Engineering, Rensselaer Polytechnic Institute, 2123 Biotech Building, 110 8th Street, Troy, NY 12180
Multi-Scale Characterization of Biomaterial-Hepatocyte Interactions Using Kinetic Fluorimetry and Microscopy Image Analysis
Jeremiah Whittenton, Rashmi Sundararajan and Adam Capitano, Chemical Engineering, University of Houston, 4800 Calhoun Rd, Houston, TX 77204
Application of Microarrays to Reverse Engineer Attachment Dependence in Mammalian Cell Lines
Pratik Jaluria, Chemical & Biomolecular Engineering, Johns Hopkins University & National Institutes of Health, 9000 Rockville Pike, Building 14A/Room 176, Bethesda, MD 20892, Michael Betenbaugh, Johns Hopkins University, 3400 N. Charles Street, 221 Maryland Hall, Baltimore, MD 21218, Konstantinos Konstantopoulos, Johns Hopkins University, 221 Maryland Hall, 3400 North Charles Street, Baltimore, MD 21218 and Joseph Shiloach, Biotechnology Unit (OD), National Institute of Diabetes, Digestive, and Kidney Diseases, 9000 Rockville Pike, Building 14A/Room 176, Bethesda, MD 20892

Food, Pharmaceutical & Bioengineering Division