Preliminary Program subject to change
15D01 Advances in Metabolic Engineering and Bioinformatics: Eukaryotes
OverviewThis session will focus on recent progress in the area of Metabolic Engineering and Bioinformatics, encompassing the development of new experimental and theoretical tools applicable to Metabolic Engineering. Topics of interest include: reconstruction of metabolic as well as gene regulatory pathways; metabolic regulation; and control analysis. Both novel theoretical approaches and experimental applications of genomic and proteomic techniques are welcomed. We invite papers on the application of these techniques to eukaryotes for biochemical and biomedical applications.
Primary SponsorEngineering Fundamentals in Life Science (15d)

Chair

Christina Chan
Associate Professor
Michigan State Uiversity
2527 Engineering Building
East Lansing, MI 48824
Phone Number: (517) 432-4530
Fax Number: (517) 432-1105
Email: krischan@egr.msu.edu

CoChair

Carolyn WT Lee-Parsons
Assistant Professor
Northeastern University
342 Snell Engineering Center
360 Huntington Avenue
Boston, MA 02115-5000

Phone Number: 617-373-3634
Fax Number: 617-373-2209
Email: clee@coe.neu.edu
Increasing Flavonoid Production by Metabolic Pathway Engineering in Multiple Yeast Hosts
Hanxiao Jiang, Purdue University, 117A, FRNY, 480 Stadium Mall Dr., West Lafayette, IN 47907 and John A. Morgan, School of Chemical Engineering, Purdue University, 480 Stadium Mall Dr., FRNY Hall, West Lafayette, IN 47907
Quantitative Target Identification for Metabolic Engineering of Yeast Saccharomyces Cerevisiae: Impacts of Bioreactor Environment
Liqing Wang and Vassily Hatzimanikatis, Department of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Road, Room E136, Evanston, IL 60208-3120
Metabolic Profiling and Flux Analysis of in Vitro Adipogenesis
Yaguang Si1, Ryan P. Nolan1 and Kyongbum Lee2, (1)Tufts University, 4 Colby Street, Medford, MA 02155, (2)Tufts University, 4 Colby Street, Room 142, Medford, MA 02155, U.S.A.
Adipocyte Metabolic Engineering for Increased Fatty Acid Oxidation through Uncoupling Protein over-Expression
Arul Jayaraman1, Santosh Palani1, Yaguang Si2 and Kyongbum Lee3, (1)Texas A&M University, Department of Chemical Engineering, 3122 TAMU, College Station, TX 77840, (2)Tufts University, 4 Colby Street, Medford, MA 02155, (3)Tufts University, 4 Colby Street, Room 142, Medford, MA 02155, U.S.A.
Intermission
A Comprehensive Insulin Signaling Model for Predicting Phenotypes Using Expression Data
Ganesh Sriram, Human Genetics & Chemical Engineering, University of California, Los Angeles, 695 Charles E. Young Dr. S. #5335, Los Angeles, CA 90095, James C. Liao, Chemical Engineering, University of California, Los Angeles, 5531 Boelter Hall, 420 Westwood Plaza, Los Angeles, CA 90095 and Katrina M. Dipple, Human Genetics & Pediatrics - David Geffen School of Medicine, University of California, Los Angeles, 695 Charles E. Young Dr. S. #5335, Los Angeles, CA 90095
Optimization and Control of Metabolic Activities in Hepatocytes
Marianthi G. Ierapetritou1, Nripen S. Sharma2, Hong Yang1, Stephen A. Guzikowski1, Martin L. Yarmush3 and Charles M. Roth4, (1)Chemical and Biochemical Engineering, Rutgers University, Rutgers University Chemical Engineering 98 Brett Road, Piscataway, NJ 08854, (2)Rutgers University, 98, Brett Road, C-252, engineering building, Piscataway, NJ 08854, (3)Biomedical Engineering, Rutgers University, Rutgers University Chemical Engineering 98 Brett Road, Piscataway, NJ 08854, (4)Department of Chemical & Biochemical Engineering, Rutgers University, 98 Brett Road, Piscataway, NJ 08854
Dynamic Metabolic Flux Analysis for Tissue Systems
Korkut Uygun, Chemical Engineering and Materials Science, Wayne State University, 5050 Anthony Wayne Dr., ENG 1128, Detroit, MI 48202, Howard W. Matthew, Wayne State University, Dept. of Chemical Engineering and Materials Science, 5050 Anthony Wayne Drive, Detroit, MI 48202 and Yinlun Huang, Department of Chemical Engineering and Materials Science, Wayne State University, 5050 Anthony Wayne Drive, Detroit, MI 48202

Food, Pharmaceutical & Bioengineering Division