Preliminary Program subject to change
15D07 Stem Cell Engineering
OverviewStem cell engineering is an emerging field in biomedicine and holds a great promise for the development of technologies that will help heal damaged tissues and replace nonfunctioning organs. One can genetically manipulate either a disorder or the immunocompatibility of stem cells due to their inherent self renewal ability. Further, recent advances in the novel property of ?plasticity? has generated immense interests in using stem cells as a cell source for regenerating tissues; by providing a conducive microenvironment i.e. cell-substrate interactions, one can regulate stem cell differentiation and proliferation to needed cell types. This adds another dimension to using stem cells ?off the shelf? for developing functionally replaceable tissues. This session will invite papers on these stem cell topics, spanning from basic quantitative cell biology to product design
Primary SponsorEngineering Fundamentals in Life Science (15d)

Chair

Sundararajan V. Madihally
Assistant Professor
School of Chemical Engineering
Oklahoma State University
423 Engineering North
Stillwater, OK 74078
Phone Number: 405-744-9115
Fax Number: 405-744-6338
Email: sundar.madihally@okstate.edu

CoChair

S. Patrick Walton
Assistant Professor
Department of Chemical Engineering and Materials Science
Michigan State University
3249 Engineering Building
East Lansing, MI 48823
Phone Number: 517-432-8733
Fax Number: 517-432-1105
Email: spwalton@egr.msu.edu
Microbioreactor Array for Controlled Differentiation of Human Embryonic Stem
Nicola Elvassore1, Sharon Gerecht-Nir2, Christopher Cannizzaro3, Robert Langer4, Gordana Vunjak-Novakovic5 and Elisa Figallo1, (1)Department of Chemical Engeneering, University of Padova, via Marzolo, 9, Padova, 35131, Italy, (2)HST, Massachusetts Institute of Technology, E25-342, 77 Massachusetts Avenue, Cambridge, MA 02139, (3)Division of Health Sciences and Technology, Massachusetts Institute of Technology, E25-342, 77 Massachusetts Avenue, Cambridge, MA 02139, (4)Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Room 66-525, Cambridge, MA 02139, (5)M.I.T., E25-342, Cambridge, MA 02142
Effects of Oxygen on Murine Embryonic Stem Cell Energetics and Growth
Daryl E. Powers, Massachusetts Institute of Technology, 77 Massachusetts Ave., Room 66-457, Cambridge, MA 02139, Ryan B. Huang, Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139 and Clark K. Colton, Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139
Influence of Matrix Architecture on Esc Differentiation and Proliferation
Yan Huang, Mbonda Siewe and Sundararajan V. Madihally, School of Chemical Engineering, Oklahoma State University, 423 Engineering North, Stillwater, OK 74078
Intermission
Induction of Embryonic Stem Cells into Endoderm Hepatic Lineage
Cheul H. Cho, Natesh Parashurama, Mara L. Macdonald, Arno W. Tilles, Francois Berthiaume and Martin L. Yarmush, Center for Engineering in Medicine, Harvard Medical School, 51 Blossom St, Boston, MA 02114
Lineage Switching of Hematopoietic Cells in Response to Changes in Culture Conditions
Li Ting Huang, Chi Chen, E. Terry Papoutsakis and William M. Miller, Chemical & Biological Engineering, Northwestern University, 2145 Sheridan Road, E136, Evanston, IL 60201
Differentiation Characteristics of Bone Marrow Derived Mesenchymal Stem Cells on Immobilized Glycosaminoglycans
Basak Saygili, Wayne State University, 5050 Anthony Wayne Drive Room 1100, Detroit, MI 48202 and Howard W.T. Matthew, Chemical Engineering and Materials Science, Wayne State University, 5050 Anthony Wayne Drive Room 1100, Detroit, MI 48202

Food, Pharmaceutical & Bioengineering Division