Preliminary Program subject to change
15D10 Advances in Drug Delivery: Hydrogels and Fibrin gels
OverviewThis session focuses on the design and development of novel drug delivery systems for targeted and/or sustained drug delivery. Topics of interest include, but are not limited to: Effects of chemical structure and/or physical properties of drug delivery systems on loading efficiency and release kinetics; blood circulation time and biodistribution of drug-carrier complexes after systemic injection; in vitro and in vivo studies of cellular uptake. This session is complementary to the general session 15b02 (Advances in Drug Delivery) and to session 15b03 (Drug Delivery across Biological Barriers. The latter focuses on biological interactions with the delivery system, and we focus on the nature and function of the delivery system itself.
Primary SponsorEngineering Fundamentals in Life Science (15d)
Co-Sponsor(s)Pharmaceuticals (15b)

Chair

Stelios C. Tsinontides
Director
Global Process Development
Cephalon, Inc.
145 Brandywine Parkway
West Chester, PA 19380
Phone Number: 610 883-5659
Fax Number: 610 738-6315
Email: stsinont@cephalon.com

CoChair

Tony J. Meehan
Director, Pharmaceutical Development
TransForm Pharmaceuticals, Inc.
29 Hartwell Ave
Lexington, MA 02421
Phone Number: 781 674 7949
Fax Number: 781 863 6519
Email: tmeehan@transformpharma.com
Antiproteolytic Action of Low-Dose Insulin Delivered Orally Using pH-Responsive Hydrogels
Angela Pantelogianis, Harvard Medical School, Shriners Hospital for Children, and Massachusetts General Hospital, 51 Blossom Street, Boston, MA 02115, Sundararajan V. Madihally, School of Chemical Engineering, Oklahoma State University, 423 Engineering North, Stillwater, OK 74078 and Mehmet Toner, Harvard Medical School and Massachusetts General Hospital, 114 16th Street Room 1238, Charlestown, MA 02129
Mucoadhesive Oral Insulin Delivery Systems Using Lectin Functionalized Complexation Hydrogels
Kristy M. Wood, Biomedical Engineering, University of Texas at Austin, 1 University Station C0400, Austin, TX 78712 and Nicholas A. Peppas, Department of Chemical Engineering, CPE 3.466, 1 University Station, Code C0400, Austin, TX 78712
Enhanced Protein Delivery from Photopolymerized Hydrogels
Chien Chi Lin, Department of Bioengineering, Clemson University, 127 Earle Hall, Clemson, SC 29634-0909 and Andrew T. Metters, Department of Chemical and Biomolecular Engineering, Clemson University, 127 Earle Hall, Clemson, SC 29634-0909
A Self-Folding Hydrogel Device for Oral Drug Delivery
hongyan He1, jingjiao Guan1, Derek Hansford2 and James Lee3, (1)Ohio State University, 140 west 19th. Ave., Columbus, OH 43210, (2)Ohio State University, 273 BEVIS HALL,1080 CARMACK ROAD, Columbus, OH 43210, (3)Chemical and Biomolecular Engineering, The Ohio State University, Room 125A, Koffolt Labs., 140W. 19th Ave., Columbus, OH 43210
Intermission
Diffusive and Convective Transport of Proteins in Fibrin Gels
Jess V. Nauman, Carnegie Mellon University, 5000 forbes Ave., Pittsburgh, PA 15213, Phil G. Campbell, Carnegie Mellon University, 5000 Forbes Ave., Pittsburgh, PA 15213, Frederick Lanni, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213 and John L. Anderson, Case Western Reserve University, Adelbert Hall 216, 10900 Euclid Avenue, Cleveland, 44106-7001
Optimization of Parameters for Sustained Local Drug Delivery of Statins for the Prevention of Vascular Intimal Hyperplasia
Anusha Vishwanathan, Biomedical Engineering, University of Akron, 260 S Forge St, Akron, OH 44325-0302, Stephanie T. Lopina, The University of Akron, The Department of Chemical Engineering and Biomedical Engineering, Akron, OH 44325, Steven P. Schmidt, Summa Health System, 525 E Market St, 3rd Floor Admin, Rm 317, Akron, OH 44304, Michelle Evancho-Chapman, Summa Health System, 525 E Market St, 3 rd floor Admin, Rm 317, Akron, OH 44304, Deenu G. Kanjickal, University of Akron, 433 Allyn st, Apt #2, Akron, OH 44304 and Aadithya Krishnan, Biomedical Engineering, University of Akron, 260 S Forge St, Olson Research Bldg 301, Akron, OH 44325-0302
Ophthalmic Antihistamine Delivery Via Recognitive Contact Lenses for Allergic Relief
Siddarth Venkatesh, Stephen P. Sizemore and Mark E. Byrne, Biomimetic & Biohybrid Materials, Biomedical Devices, and Drug Delivery Laboratories, Department of Chemical Engineering, Auburn University, Auburn, AL 36849-5127

Food, Pharmaceutical & Bioengineering Division