Preliminary Program subject to change
15D12 Transport Phenomena in Tissue Engineering
OverviewThe field of tissue engineering seeks to create clinically effective materials for the repair of damaged tissues and organs and the treatment of medical conditions brought on by trauma, disease or congenital defects. Tissue engineering strategies involve the incorporation of novel biomaterials with biologics and/or pharmaceutics, that upon implantation in the patient will stimulate angiogenesis, tissue integration, and/or tissue remodeling. Critical to the development of effective tissues is the regulation of transport phenomena. This includes delivery of oxygen, nutrients, transforming factors, genes, and cryoprotectants to cells, clearance of metabolic waste products, and intercellular communication via autocrine and paracrine factors. Concurrently, transport of cells represents another challenging component of tissue engineering and important considerations include the migration of cells through scaffolds and their spatial organization into tissue structures. This session seeks a broad range of research abstracts that encompass both experimental and computational aspects of transport phenomena. Tissues include but are not limited to liver, pancreas, retina, muscle, skin, tendon, cartilage, bone, vascular, and nerve.
Primary SponsorEngineering Fundamentals in Life Science (15d)

Chair

Aaron S. Goldstein
Assistant Professor
Department of Chemical Engineering, 0211
Virginia Tech
Blacksburg, VA 24061-0211
Phone Number: 540-231-3674
Fax Number: 540-231-5022
Email: goldst@vt.edu

CoChair

Vassilios I. Sikavitsas
Assistant Professor
The University of Oklahoma
School of Chemical, Biological, and Materials Engineering
100 East Boyd, Room T335
Norman, OK 73019
Phone Number: (405)-325-1511
Fax Number: (405)-325-5813
Email: vis@ou.edu
Mass Transfer Rates and Initial Conditions Modulate the Growth Rates and Structure of Bioartificial Tissues
Kyriacos Zygourakis1, Jian Feng2 and Pauline A. Markenscoff2, (1)Dept. of Chemical and Biomolecular Engineering, Rice University, MS-362, P. O. Box 1892, Houston, TX 77251-1892, (2)Department of Electrical and Computer Engineering, University of Houston, Houston, TX 77204-4793
Strategies to Enhance Capillary Formation inside Biomaterials: a Computational Study
Ehsan Jabbarzadeh, Drexel University, 2215 arch street, Apt 314, Philadelphia, PA 19103 and Cameron F. Abrams, Drexel University, Department of Chemical Engineering, Philadelphia, PA 19104
Traceable Hil2 Secretion in Enyzme Crosslinked Gelatin Cellular Scaffolds
Chong Wing Yung, Chemical and Biomolecular Engineering, University of Maryland, College Park, 6143 Plant Science Bldg, College Park, MD 20742, Timothy Barbari, Department of Chemical and Biomolecular Engineering, University of Maryland, College Park, MD 20742-2111, William E. Bentley, Chemical and Biomolecular Engineering, University of Maryland, 5115 Plant Sciences Building, College Park, MD 20742 and Gregory F. Payne, Center for Biosystems Research, UMBI, Plant Sciences Bldg. Room 6138, College Park, MD 20742
Modulation of Liver Functions Expressed by Hepg2 Cells by Limiting Oxygen Diffusion
James P. Camp and Adam T. Capitano, Chemical Engineering, University of Houston, S222 Engineering Bldg 1, Houston, TX 77204-4004
Intermission
Perfluorocarbons for Enhanced Oxygen Transport in Tissue Engineering Devices
Kyuongsik Chin, Surita R. Bhatia and Susan C. Roberts, Chemical Engineering, University of Massachusetts, Amherst, 686 North Pleasant Street, Amherst, MA 01003
Protection of Microencapsulated Islets from Hypoxia by Perfluorocarbon
Amy S. Lewis1, Robert J. Fisher1, Abdulkadir Omer2, Gordon C. Weir2 and Clark K. Colton1, (1)Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, (2)Section on Islet Transplantation and Cell Biology, Joslin Diabetes Center, Harvard Medical School, One Joslin Place, Boston, MA 02215
Characteristics of Btc Tet Cells for Use in the Cryopreservation of a Model Tissue Engineered Pancreatic Substitute
Indra Neil Mukherjee1, Ying Ching Song2 and Athanassios Sambanis1, (1)Chemical & Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Drive, Atlanta, GA 30332-0100, (2)Cell and Tissue Systems, Inc., 701 East Bay St, Suite 433, MSC 1119, Old Cigar Factory, Charleston, SC 29403

Food, Pharmaceutical & Bioengineering Division