Preliminary Program subject to change
15D14 Biomolecular Interactions in Intracellular Processes
OverviewProper cellular function depends on specifically regulated biomolecular interactions. Thus, the understanding of intracellular processes requires thorough analysis of the contributions of small molecule and macromolecule cellular components. Presentations for this session should focus on theoretical and experimental methods for the analysis of intracellular processes and, in particular, the extracellular and intracellular biomolecular interactions that contribute. Talks focusing on metabolic regulation, transcriptional and translational control of gene expression, and signal transduction are of interest. In addition, talks covering modification of the cellular network through methods such as antisense and RNAi, and in particular, those utilizing large-scale genomic and proteomic analyses for the understanding of the global cellular network will be strongly considered.
Primary SponsorEngineering Fundamentals in Life Science (15d)

Chair

S. Patrick Walton
Assistant Professor
Department of Chemical Engineering and Materials Science
Michigan State University
3249 Engineering Building
East Lansing, MI 48823
Phone Number: 517-432-8733
Fax Number: 517-432-1105
Email: spwalton@egr.msu.edu

CoChair

Arul Jayaraman
Assistant Professor
Texas A&M University
Department of Chemical Engineering
3122 TAMU
College Station, TX 77840
Phone Number: 617-371-4874; 979-845-3361
Fax Number: 979-845-6446
Email: arul.jayaraman@chemail.tamu.edu
Signal Transduction at Point-Blank Range: a Brownian Dynamics Study
Michael Monine and Jason Haugh, Chemical & Biomolecular Engineering, North Carolina State University, Raleigh, NC 27695-7905
Effect of Nutrient Fluxes on Osteoblast Culture Survival
Agnes Ostafin, University of Notre Dame, Dept of Chemical & Biomolecular Engineering, Notre Dame, IN 46556, Stephanie M. Schmidt, Chemical & Biomolecular Engineering, University of Notre Dame, 182 Fitzpatrick Hall, Notre Dame, IN 46556-5637 and Mark J. McCready, Chemical and Biomolecular Engineering, University of Notre Dame, 182 Fitzpatrick Hall, Notre Dame, IN 46556
Elucidation of Intracellular Signaling Pathways in Shear-Activated Chondrocytes: a Role in Arthritis
Zachary R. Healy, Johns Hopkins University, 3400 N Charles Street, Baltimore, MD 21218, Norman Lee, Molecular Biololgy and Functional Genomics, The Institute for Genomic Research, 9700 Medical Center Drive, Rockville, MD 21085, Paul Talalay, Pharmacology, Director of the Laboratory for Molecular Sciences, Johns Hopkins University - School of Medicine, 725 N Wolfe Street, Baltimore, MD 21205, Thomas Kensler, Toxicology, Johns Hopkins University - School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205 and Konstantinos Konstantopoulos, Johns Hopkins University, 221 Maryland Hall, 3400 North Charles Street, Baltimore, MD 21218
The Role of Jnk Signaling in Cell-Cell Adhesion and Differentiation of Epithelial Cells: Implications for Tissue Engineering of Stratified Epithelium
Piyush Koria, SUNY at Buffalo, 916 Furnas Hall, Amherst, NY 14260 and Stelios T. Andreadis, SUNY at Buffalo, 908 Furnas Hall, Amherst, NY 14260
Intermission
Single Molecule Kinetics of Reverse Transcriptase
Charles M. Schroeder, Sangjin Kim, Paul C. Blainey and X. Sunney Xie, Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138
Real-Time Visualization of One-Dimensional Diffusion of a Fluorescently Labeled Protein along Single DNA Molecules Aligned on a Surface
Ji Hoon Kim, Chemical Engineering, University of Michigan, 2300 Hayward St., 3074 H.H.DOW Building, Ann Arbor, MI 48109 and Ronald G. Larson, University of Michigan, Department of Chemical Engineering, Ann Arbor, MI 48109
Key Components for Transport through the Nuclear Pore Complex (Npc): Mechanisms Involved during Binding between Specific Karyopherins and Fg-Nups
Antoine Bouchoux1, Amit Dutta1 and Georges Belfort2, (1)Howard P. Isermann Department of Chemical Engineering, Rensselaer Polytechnic Institute, 110 8th Street, TROY, NY 12180, (2)Rensselaer Polytechnic Institute, 110 8th St., Ricketts Bldg,, Troy, NY 12180

Food, Pharmaceutical & Bioengineering Division