Cartridge Filter Separation System: an Alternative to Column Chromatography in Downstream Purification of Protein Therapeutics Masayuki Nakamura1, Kelly J. Gibbens2, Robert T. Fitzsimons2, Andrew W. Rabins2, Kannan Seshadri2, Steve M. Larsen2, Douglas A. Hanggi2, Catherine A. Bothof2, Larry J. Carson2, Gustov H. Castro2, James I. Hembre2, Patrick L. Coleman2, Jarald K. Rasmussen2 and Steven M. Heilmann2, (1)Corporate Research Lab, 3M, 3M Center, 201-2E-08, St. Paul, MN 55144, (2)3M, 3M Center, 201-2E-08, St. Paul, MN 55144 |
Functionalized Nanoporous Molecular Sieves for Chromatographic Separations of Proteins Amit Katiyar, University of Cincinnati, P.O. Box 210012, Cincinnati, OH 45221-0012, Panagiotis (Peter) Smirniotis, University of Cincinnati, Chemical & Materials Engineering Department, P.O. Box 210012, Cincinnati, OH 45221-0012 and Neville G. Pinto, Chemical & Materials Engineering, University of Cincinnati, P.O. Box 210012, Cincinnati, OH 45221-0012 |
Protein C Purification Using Pc Specific Mini-Mab from the Inexpensive Source, Cohn Blood Plasma Fraction VI-1 Samin Rezania1, Doh Gyeuhn Ahn2 and Kyung A. Kang2, (1)University of Louisville, 106 EH Dept. of Chem. Eng., University of Louisville, Louisville, KY 40292, (2)Chemical Engineering, University of Louisville, 106 EH Dept. of Chem. Eng., University of Louisville, Louisville, KY 40292 |
Investigation of Protein Adsorption and Similarity Measurement for Protein Binding Behavior in Hydrophobic Interaction Chromatography (Hic) System Jie Chen1, Qiong Luo2, Matthew C. Sundling2, Abigail H. Laurent3, Jace L. Fogle4, Yunzhi Xiao4, Curt M. Breneman2, Erik J. Fernandez4, Todd M. Przybycien3 and Steven M. Cramer1, (1)Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, 110 8th St., Troy, NY 12180, (2)Department of Chemistry, Rensselaer Polytechnic Institute, 110 8th St., Troy, NY 12180, (3)Department of Chemical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, (4)Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22904 |
Intermission |
Resolution of Racemic Mixtures Coupling Crystallization and Simulated Moving Bed: Fundamental Studies for S-Ketamine Production Georgia O. F. Barros and Everson A. Miranda, Biotechnology, UNICAMP - School of Chemical Engineering, Albert Einstein St., Campinas, Brazil |
Mutants of Phenylalanine Dehydrogenase: New Bio-Catalysts in the Asymmetric Synthesis and Racemic Resolution of Non-Natural Aminocids Paul C. Engel1, Francesca Paradisi2, Eamonn Moynihan3 and Anita R. Maguire3, (1)Department of Biochemistry, University College Dublin, Conway Institute of Biomolecular and Biomedical Research, Belfield Campus, Dublin, 4, Ireland, (2)Department of Biochemistry, University College Dublin, Conway Institute, Belfield Campus, Dublin, 4, Ireland, (3)Department of Chemistry, University College Cork, Cork, Ireland |
Molecular Mechanisms of Selective Sorption of Chiral Enantiometers on Amylose-Based Sorbents Rahul B. Kasat, School of Chemical Engineering, Purdue University, 480 Stadium Mall Drive, West Lafayette, IN 47907-2100, Kendall Thomson, Purdue University, School of Chemical Engineering, 480 Stadium Mall Drive,, West Lafayette, IN 47907-2100, Hugh W. Hillhouse, Purdue University, 1283 CHME BLD, West Lafayette, IN 47907, Linda Wang, Purdue University, School of Chemical Engineering, 1283 Chemical Engineering Building, West Lafayette, IN 47907-1283 and Elias I. Franses, Purdue University, 480 Stadium Mall Drive, West Lafayette, IN 47907-2100 |