Preliminary Program subject to change
T3024 Multiscale Modeling of Biological Processes and Systems
OverviewWith continuously increasing computational methods, modeling and simulation are becoming powerful tools in biological research. Modeling and simulation in biology possess significant challenges and one of the main challenges is relating behavior at the nano- or micro-level to properties at the macro-level. These multi-scale challenges are critical to the future of systems biology. Systems biology seeks to gain a further understanding of biological systems by describing the integrated function of many genes or proteins, and the implications for complex macro-scale phenomena such as disease states. Our knowledge of the properties of proteins and genes at the nano-level is growing rapidly due to the great successes of hypothesis driven reductionist research. Now, multi-scale modeling algorithms, techniques, mathematical theories are needed that will increase our understanding of multi-scale phenomena in biological systems. This session will focus on the development of these tools with applications in biology.
Primary SponsorTopical 3 - Multiscale Analysis in Chemical, Materials and Biological Processes (T3)

Chair

Francis J Doyle III
Professor
UCSB
Department of Chemical Engineering
Santa Barbara, CA 93106

Phone Number: (805) 893-8133
Fax Number: (805) 893-4731
Email: doyle@engineering.ucsb.edu

CoChair

Jeremy Edwards


Email: edwards@che.udel.edu
Implications of Spatial Organization of Epidermal Growth Factor Receptors
Kapil Mayawala1, Dionisios Vlachos1 and Jeremy S. Edwards2, (1)Department of Chemical Engineering, University of Delaware, 150 Academy Street, Newark, DE 19716, (2)Molecular Genetics and Microbiology, Cancer Research and Treatment Center, UNM Health Sciences Center, Chemical and Nuclear Eng, University of New Mexico, Albuquerque, NM
Propagation of Signals within a Collection of Cells
J. Panovska, Chemical Engineering, Heriot-Watt University, School of Engineering and Physical Sciences,, Edinburgh, United Kingdom, A. Kummer, Chemical Engineering, Heriot-Watt University, School of Engineering and Physical Sciences, Edinburgh, EH14 4AS and R. Ocone, Chemical Engineering, Heriot-Watt University, School of Engineering and Physical Sciences,, Edinburgh, EH14 4AS, United Kingdom
Dynamics of Heterogeneous Cell Populations Growing under Transport Limitations: a Hybrid, Multi-Scale Model
Jian Feng1, Pauline A. Markenscoff1 and Kyriacos Zygourakis2, (1)Department of Electrical and Computer Engineering, University of Houston, Houston, TX 77204-4793, (2)Rice University, Dept. of Chemical and Biomolecular Engineering, MS-362, P. O. Box 1892, Houston, TX 77251-1892
Model Reduction of Multi Scale Chemical Langevin Equations
Marie-Nathalie Contou-Carrere1, Prodromos Daoutidis1 and Yiannis Kaznessis2, (1)University of Minnesota, Chemical Engineering and Materials Science Department, 151 Amundson Hall, Minneapolis, MN 55455-0132, (2)University of Minnesota, 151 Amundson Hall, Minneapolis, MN 55455-0132
Multiscale Stochastic Simulations of the Mitogen Activated Protein (Map) Kinase Cascade
Asawari Samant1, Abhijit Chatterjee2 and Dionisios G. Vlachos1, (1)University of Delaware, Department of Chemical Engineering, 150 Academy St., 325 Colubrn Lab, Newark, DE 19716, (2)Department of Chemical Engineering, University of Delaware, 353 Colburn Lab, Academy Street, Newark, DE 19716
Multiscale Analysis of Feedback Control in Epithelial Patterning Systems
Gregory T. Reeves1, Cyrill B. Muratov2 and Stas Shvartsman1, (1)Department of Chemical Engineering and Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, (2)Department of Mathematical Sciences, New Jersey Institute of Technology, Newark, NJ 07102
Interaction between DNA Molecules and Fullerenes: Molecular Dynamics Study
Xiongce Zhao, Nanomaterials Theory Institute, Center for Nanophase Materials Sciences, Oak Ridge National Laboratory, Oak Ridge, TN 37831, Alberto Striolo, Vanderbilt University, 118 Olin Hall, Nashville, TN 37235 and Peter T. Cummings, Vanderbilt University, Department of Chemical Engineering, VU Station B 35160, Nashville, TN 37235-1604

Topical 3 - Multiscale Analysis in Chemical, Materials and Biological Processes