Preliminary Program subject to change
TA008 New Developments in Bioanalytical CE and Microdevice Technology
OverviewElectrophoresis is proven to be an invaluable and powerful tool in the bioanalytical research areas of genetic analysis, pharmaceutical development, and protein characterization. Advances in these areas have been forwarded by enhancement of the basic electrophoretic format such as sample focusing techniques, novel replaceable physical gels, and secondary separation methods using advantageous additives such as surfactants or chiral selective molecules in the run buffer. Further, advances in microfabrication have made it possible to implement these standard capillary electrophoresis techniques on microdevice formats, with potential improvements including high throughput, reduced cost, small sample requirements and the lure of portability. This session will focus on technical aspects of the development and improvement of CE and electrophoretic microdevice platforms for the efficient separation of DNA, proteins, and other biomolecules for enhanced bioanalysis, with an emphasis on integrated sample preparation, unique replaceable gel formulations, microchannel surface functionalization, secondary separation mechanisms, and microdevice design.
Primary SponsorTopical A - American Electrophoresis Society Annual Meeting (TA)

CoChair

Rebecca A. Zangmeister
Staff Scientist
National Institute of Standards and Technology
100 Bureau Dr
MS 8362
Gaithersburg, MD 20899-8362
Phone Number: 301.975.4912
Fax Number: 301.978.2643
Email: razang@nist.gov

CoChair

Gloria Thomas
Assistant Professor
Department of Chemistry
Mississippi State University
Mississippi State, MS 39762
Phone Number: 662-325-5492
Email: gthomas@chemistry.msstate.edu
Plenary: Scanning Temperature Gradient Focusing for Simultaneous Concentration and Separation of Complex Samples
David Ross, Karin M. Balss, Stacey J. Hoebel, Barbara J. Jones, Constantin Malliaris and Wyatt N. Vreeland, NIST, 100 Bureau Dr, Gaithersburg, MD 20902
Sequence Specific Separation of Target DNA in Micellar Electrokinetic Chromatography
Shane T. Grosser and James W. Schneider, Chemical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213
New Approaches to Genotyping with End-Labeled Free Solution Electrophoresis
Robert J. Meagher1, Russell D. Haynes1, Jennifer Lin1, Jong-In Won2 and Annelise E. Barron1, (1)Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Road - TECH E136, Evanston, IL 60208, (2)Chemical Engineering, Hongik University, Seoul, South Korea
A Microfluidic Platform for Rapid Screening of Separation Performance in Gel Matrices for DNA Electrophoresis
Roger C. Lo, Rene' D. Elms and Victor M. Ugaz, Chemical Engineering, Texas A&M University, 3122 TAMU, College Station, TX 77843
Development of Polymeric Microchips for Use in Binding Studies
April L. Dupre1, Wendy D. Dominick1, Justin S. Mecomber1, H. Brian Halsall1, William R. Heineman1, Carl J. Seliskar1, Kenneth R. Wehmeyer2 and Patrick A. Limbach1, (1)Chemistry, University of Cincinnati, PO Box 210172, Cincinnati, OH 45221, (2)Analytical Sciences, Procter and Gamble Pharmaceuticals, 8700 Mason-Montgomery Rd, Mason, OH 45040
Ultra-Fast DNA Sequencing by Microchannel Electrophoresis with a Dynamic Coating: 540 Bases in 4.5 Minutes
Christopher P. Fredlake, Cheuk-Wai Kan, Daniel G. Hert and Annelise E. Barron, Department of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208
Two Dimensional Micro Gel Electrophoresis Device with Integrated Removeable Capillary Insert (Rci) for Macro-Micro Interface and Post Separation Sample Manipulation
Swomitra Mohanty1, Javier Atencia1, Jack Gorski2 and David J. Beebe1, (1)Department of Biomedical Engineering, University of Wisconsin-Madsion, 1550 Engineering Drive, Madison, WI 53706, (2)Blood Institute of Southeastern Wisconsin, Milwaukee, WI 53233

Topical A - American Electrophoresis Society Annual Meeting