Preliminary Program subject to change
15B07 Advances in Drug Delivery: Microparticles
OverviewThe engineering of micronized and nanoscale particles, or suitable particulate devices is essential in facilitating mechanisms for drug delivery such as increasing the bioavailability of molecules, as well as allowing them to be targeted to specified sites. Controlling the particle morphologies of physiologically active powders can improve their transport and stability in suspension or in the dry state. Experimental and theoretical papers are invited concerning the synthesis, properties, and applications of microparticulate drug delivery devices. Areas may include microencapsulation, liposomes, particle engineering, supercritical fluid processes, novel polymerizations, biomimetics, pharmaceutical dosage forms,and related fields.
Primary SponsorPharmaceuticals (15b)
Co-Sponsor(s)Engineering Fundamentals in Life Science (15d)

Chair

Padma J. Narayan
Principal Scientist
Pfizer, Inc.
Pharmaceutical R&D, MS 8156-41
Eastern Point Rd
Groton, CT 06340
Phone Number: (860) 686-1199
Fax Number: (860) 441-3972
Email: padma.narayan@pfizer.com

CoChair

Suhas D. Shelukar
Senior Research Fellow
Merck Research Laboratories
Merck and Co., Inc.
PO Box 4, WP78-204
West Point, PA 19486
Phone Number: 215-652-2119
Fax Number: 215-652-4088
Email: suhas_shelukar@merck.com
Supercritical CO2 Based Formation of Drugs and Proteins Nanoparticles and Microencapsulation for Sustained Release
Amol J. Thote, Kayoko Ono and Ram B. Gupta, Chemical Engineering, Auburn University, 0322 Haley Center, Auburn, AL 36849-5127
Dry Powder Aerosols for Multi-Drug Resistant Tuberculosis (Mdr-Tb) Treatment
Jennifer Fiegel1, Lucila Garcia-Contreras2, Katharina Elbert1, Anthony Hickey2 and David Edwards1, (1)Division of Engineering and Applied Sciences, Harvard University, 40 Oxford St., Cambridge, MA 02138, (2)School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599
Monodisperse Powders for Controlled Release Inhalation Therapy
Cory Berkland, Chemical and Petroleum Engineering/ Pharmaceutical Chemistry, University of Kansas, B53 Smissman, 2095 Constant Avenue, Lawrence, KS 66047 and Matthew Arnold, Chemical and Petroleum Engineering, University of Kansas, 4132 Learned Hall, 1530 W. 15th St., Lawrence, KS 66045
Long-Circulating Nanoparticles through Red Blood Cell Attachment
Elizabeth L. Chambers, Chemical Engineering, University of California, Santa Barbara, Engineering II Room 3229, Santa Barbara, CA 93106-5080 and Samir Mitragotri, University of California, Santa Barbara, CA unknown
Intermission
Analysis of Transient Protein Distribution in Plga Microparticles during Polymer Degradation and in Vitro Release
Aiying Zhao and Victor G.J. Rodgers, Chemical Engineering, The University of Iowa, Iowa City, IA 52242
Incorporating Eg Chains into Polyanhydrides: Consequences for Protein Stabilization and Delivery
Maria P. Torres, Chemical & Biological Engineering, Iowa State University, 2147 Sweeney, Ames, IA 50011, Balaji Narasimhan, Chemical & Biological Engineering, Iowa State University, 2035 Sweeney, Ames, IA 50011 and Surya K. Mallapragada, Chemical & Biological Engineering, Iowa State University, 144 Spedding Hall, Ames, IA 50011
Particle Design for Enhanced Dissolution Rates of Poorly Water Soluble Drugs
Keith Johnston1, Xiaoxia Chen2, Jason McConville3, Jason Vaughn3, Kirk Overhoff3, Michal Matteucci2, Matthew Crisp2 and Robert Williams3, (1)University of Texas Austin, 1 University Station C0400, Austin, TX 78712, (2)Dept. Chemical Engineering, University of Texas Austin, 1 University Station C0400, Austin, TX 78712, (3)College of Pharmacy, University of Texas Austin, 1 University Station C0400, Austin, TX 78712

Food, Pharmaceutical & Bioengineering Division