Preliminary Program subject to change
15D21 Culture Strategies to Enhance Engineered Tissue Phenotype
OverviewThe field of tissue engineering seeks to create clinically effective materials for the repair of damaged tissues and organs and the treatment of medical conditions brought on by trauma, disease or congenital defects. Tissue engineering strategies involve the incorporation of novel biomaterials with biologics and/or pharmaceutics, that upon implantation in the patient will stimulate angiogenesis, tissue integration, and/or tissue remodeling. Critical to the development of effective tissues are strategies that enhance phenotypic markers of the target tissue, and may include approaches that regulate cell adhesion, intercellular communication, activation of receptor-mediated signaling pathways, or mechanotransduction. This session seeks abstracts that describe novel in vitro strategies to enhance phenotypic markers of engineered tissues, including (but not limited to) liver, pancreas, retina, muscle, skin, tendon, cartilage, bone, vascular, and nerve.
Primary SponsorEngineering Fundamentals in Life Science (15d)

Chair

Aaron S. Goldstein
Assistant Professor
Department of Chemical Engineering, 0211
Virginia Tech
Blacksburg, VA 24061-0211
Phone Number: 540-231-3674
Fax Number: 540-231-5022
Email: goldst@vt.edu

CoChair

Vassilios I. Sikavitsas
Assistant Professor
School of Chemical, Biological and Materials Engineering
University of Oklahoma
100 E. Boyd, Room T335
Norman, OK 73019
Phone Number: 405-325-1511
Fax Number: 405-325-5813
Email: vis@ou.edu
Investigation of Chemical Effects on Neural Progenitor Cell Adhesion and Differentiation Using Micropatterned Substrates
Erin Boote Jones1, Jennifer Recknor2, Donald S. Sakaguchi3 and Surya K. Mallapragada1, (1)Chemical Engineering, Iowa State University, Ames, IA 50011, (2)Chemical Engineering and Neuroscience Program, Iowa State University, Ames, IA 50011, (3)Genetics, Development, and Cell Biology, Iowa State University, Ames, IA 50011
Application of Micropatterning Techniques to Co-Culture Systems for Hepatic Tissue Engineering
Cheul H. Cho, Jae-Sung Park, Francois Berthiaume, Arno W. Tilles, Mehmet Toner and Martin L. Yarmush, Center for Engineering in Medicine, Harvard Medical School, 51 Blossom St, Boston, MA 02114
Preventing Hepatocyte Steatosis by Co-Culture with Adipocytes during Plasma Exposure
Deepak Nagrath1, Vanessa Lopez2, Francois Berthiaume2 and Martin Yarmush2, (1)Harvard Medical School, 51 Blossom Street, Boston, MA 02144, (2)Surgery, MGH, Boston, MA 02114
Morphological and Functional Responses of Hepatocytes Cultured on Glycosaminoglycan-Chitosan Membranes
Therese Bou-Akl, Biomedical Engineering, Wayne State University, Detroit, MI 48202, Basak Saygili, Wayne State University, 5050 Anthony Wayne Drive Room 1100, Detroit, MI 48202 and Howard W.T. Matthew, Chemical Engineering and Materials Science, Wayne State University, 5050 Anthony Wayne Drive, Detroit, MI 48202
Intermission
Using Bone-like Ecm Produced in Vitro to Influence Osteoblastic Differentiation of Marrow Stromal Cells
Upma Sharma, Quynh Pham, Neha Datta and Antonios Mikos, Bioengineering, Rice University, 6100 Keck Hall, Suite 116, Houston, TX 77005
Seeding of Scaffolds for Tissue Engineering in a Flow Perfusion Bioreactor Improves Efficiency and Cell Distribution
Jose F. Alvarez-Barreto1, Shawna Linehan1, Jessica Yankovich1, Robert L. Shambaugh2 and Vassilios I. Sikavitsas3, (1)Chemical, Biological and Materials Engineering, University of Oklahoma, 100 E. Boyd Rm T-335, Norman, OK 73019, (2)Chemical, Biological and Materials Engineering, University of Oklahoma, 100 E. Boyd Rm T335, Norman, OK 73019, (3)University of Oklahoma, School of Chemical, Biological, and Materials Engineering, 100 E. Boyd Rm T335, Norman, OK 73019
Bioreactor Optimization of Scaffold Seeding for Cartilage Tissue Engineering
Bahar Bilgen, Ericka M. Bueno and Gilda A. Barabino, Chemical Engineering, Northeastern University, 342 Snell Engineering Center, 360 Huntington Avenue, Boston, MA 02115

Food, Pharmaceutical & Bioengineering Division