Antibody Affinity Maturation Using Computational Protein Design
Shaun M. Lippow, Chemical Engineering, MIT, 32-211, Cambridge, MA 02139, Bruce Tidor, Biological Engineering; Electrical Engineering & Computer Science, MIT, Cambridge, MA 02139 and K. Dane Wittrup, Chemical Engineering; Biological Engineering, MIT, Cambridge, MA 02139 |
Ipro: Iterative Protein Redesign and Optimization Procedure: Application to Three Case-Studies
Manish C. Saraf1, Brian A. Canada1 and Costas D. Maranas2, (1)Department of Chemical Engineering, Penn State University, 147 Fenske Laboratory, University Park, PA 16802, (2)Department of Chemical Engineering, Penn State University, 112 Fenske Laboratory, University Park, PA 16802 |
An Informatics Analysis of the in Vivo Affinity Maturation Process -- Learning from Nature's Evolution of Protein-Protein Interfaces
Louis A. Clark and Herman Van Vlijmen, Biogen Idec, 14 Cambridge ctr, Cambridge, MA 02142 |
Characterization of Protein Sequence Landscapes Using Flat-Histogram Monte Carlo Algorithms
M. Scott Shell, Chemical Engineering, Princeton University, A-217 E-Quad, Princeton, NJ 08544, Pablo G. Debenedetti, Princeton University, A-217 E-Quad, Princeton, NJ 08544 and Athanassios Z. Panagiotopoulos, Princeton University, A223 Engineering Quad., Princeton, NJ 08544 |
Atomic Molecular Dynamical Modeling of a Large Protein Complex: Stf-Fviia
Coray M. Colina1, Robert E. Duke2, Divi Venkateswarlu3, Lalith Perera2, Tom Darden2 and Lee G Pedersen1, (1)Department of Chemistry, University of North Carolina, Campus Box 3290, Chapel Hill, NC 27599, (2)Laboratory of Quantitative and Computational Biology, National Institute of Environmental Health Science, Research Triangle Park, Raleigh, NC 27709, (3)Department of Chemistry, NC A&T State University, Greensboro, NC 27411 |
Unfolding a Linker between Helical Repeats
Vanessa Ortiz, Univ.Pennsylvania, 112 Towne Bldg, Philadelphia, PA 19104, Steven O. Nielsen, Department of Chemistry, University of Texas at Dallas, Dallas, TX 75080, Michael L. Klein, Chemistry, Univ.Pennsylvania, 112 Towne Bldg, Philadelphia, PA 19104 and Dennis E. Discher, Chemical and Biomolecular Engineering, Univ.Pennsylvania, 112 Towne Bldg, Philadelphia, PA 19104 |
Molecules Losing Space: an Entropy Calculation of Ache-Fas2 Association
Tushar Jain, David Minh and J. Andrew McCammon, Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093-036 |
Visualization and Characterization of Protein Conformational Space Via Geometric Techniques
Pramod P. Wangikar, Department of Chemical Engineering, Indian Institute of Technology Bombay, Dept of Chemical Eng, IIT Bombay Powai, Mumbai, 400076, India, Ashish Tendulkar, Kanwal Rekhi School of Information Technology, Indian Institute of Technology Bombay, Dept of Chemical Eng, IIT Bombay Powai, Mumbai, 400076, India and Babatunde A. Ogunnaike, University of Delaware, 150 Academy St, Newark, DE 19716 |