| This session will concentrate on the theoretical principles and practical considerations that underlie the use of membranes in the downstream processing of biopharmaceutical products (e.g. microfiltration, ultrafiltration, nanofiltration, virus filtration, and membrane chromatography). Papers describing advances in membrane processes, new membrane materials and applications, and case studies of membrane systems in the biopharmaceutical industry are sought. |
Effects of pH and Ionic Conditions on Microfiltration of Mammalian Cells: Combined Permeate Flux Enhancement and Mab Purification Capabilities
Jonathan Karl Romero, Philippe de Vilmorin and James Chrostowski, Process Development Engineering, BiogenIdec Inc, 15 Cambridge Center, Cambridge, MA 02142 |
Improving Permeate Flux in the Microfiltration of a Bacterial Cell Suspension by Flocculation with Cationic Polyelectrolytes
Matthew T. Aspelund, Chemical and Biological Engineering, Iowa State Univeristy, 2114 Sweeney Hall, Ames, IA 50011, Charles E. Glatz, Chemical and Biological Engineering, Iowa State University, 2114 Sweeney, Ames, IA 50011, Kevin M. Graves, Chemical and Biological Engineering, Iowa State University, 2114 Sweeney Hall, Ames, IA 50011, Glenn Rozeboom, Process Science, Danisco Genencor, 1000 41st Avenue Dr SW, Cedar Rapids, IA 52404 and Meng Heng, Process Science, Danisco Genencor, 925 Page Mill Road, Palo Alto, CA 94304 |
Protein Fouling of Microfiltration Membranes in in-Line Modules
Dharmesh Kanani and Raja Ghosh, Chemical Engineering, McMaster University, 1280, Main Street West, Hamilton, ON L8S 4L7, Canada |
Smart Monomers and Nature-Inspired Monomers for Protein Adhesion-Resistant Membranes
Arpan Nayak, Hongwei Liu and Georges Belfort, Howard P. Isermann Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, 110 8th st, Troy, NY 12180-3590 |
Organic-Inorganic Hybrid Membranes for Protein Purification
Daniel F. Shantz, Department of Chemical Engineering, Texas A&M University, TAMU 3122, College Station, TX 77843-3122 and Seunguk Yeu, Department of Chemical Engineeing, Texas A&M University, TAMU 3122, College Station, TX 77843-3122 |
Viral Filtration of High-Titer Mab Solutions with Hollow Fiber Membranes
Bruno F. Marques, Nihal Tugcu, M. Ellen Dahlgren, Sarah Parola and David J. Roush, BioPurification Development, Merck & Co., 126 E. Lincoln Ave., P.O. Box 2000, Rahway, NJ 07065 |
Virus Capture by Tangential Flow Filtration
Ranil Wickramasinghe, Colorado State University, Department of Chemical Engineering, Fort Collins, CO 80523-1370, David Grzenia, Chemical and Biological Engineering, Colorado State University, Fort Collins, CO 80523 and Peter Czermak, Department of Biotechnology, University of Applied Sciences Giessen Friedberg, Wiesenstrasse 14, Giessen, 35390, Germany |
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