Preliminary Program subject to change
01A09 Thermophysical Properties of Biological Systems I
OverviewThe focus of this session is the study of complex processes in biological systems. Contributions from theoreticians, simulators, and experimentalists are welcome. Suggested topics include protein-protein interactions, concentration and crowding effects on biomolecular folding and stability, misfolding and aggregation events, interactions of proteins with interfaces, and self-assembly of biological molecules.
Primary SponsorThermodynamics and Transport Properties (01a)

Chair

Donald P. Visco Jr.
Associate Professor
Chemical Engineering
Tennessee Technological University
Box 5013
Cookeville, TN 38505
Phone Number: 931-372-3606
Fax Number: 931-372-6352
Email: dvisco@tntech.edu

CoChair

Shekhar Garde
Professor
Rensselaer Polytechnic Institute
Dept of Chemical Engineering, RPI
110 8th Street
Troy, NY 12180
Phone Number: 518 276 6048
Fax Number: 518 276 4030
Email: gardes@rpi.edu
Introductory Remarks
A Computer Simulation and Theoretical Study of Hybridization in Model DNA Microarrays
Arthi Jayaraman, Department of Material Science and Engineering, University of Illinois at Urbana-Champaign, 1304 W. Green St., Urbana, IL 61801, Carol K. Hall, Department of Chemical and Biomolecular Engineering, North Carolina State University, College of Engineering 1, Box 7905, 911 Partners Way, Raleigh, NC 27695 and Jan Genzer, Chemical and Biomolecular Engineering, North Carolina State University, 911 Partners Way, Raleigh, NC 27695
Monte Carlo Simulations of the Thermal Denaturation Transition of Model DNA Chains in Solution
Juan C. Araque, Department of Chemical and Biomolecular Engineering, Rice University, 6100 Main St., Houston, TX 77025, Athanassios Z. Panagiotopoulos, Princeton University, A223 Engineering Quad., Princeton, NJ 08544 and Marc A. Robert, Chemical and Biomolecular Engineering, Rice Quantum Institute, Richard E. Smalley Institute for Nanoscale Science and Technology, Rice University, 6100 Main St., Houston, TX 77025
Unraveling the Behavior of DNA through Multiscale Modeling
Thomas A. Knotts IV, Stephan Deublein and Juan J. De Pablo, Department of Chemical and Biological Engineering, University of Wisconsin-Madison, 1415 Engineering Drive, Madison, WI 53706-1691
An Integrated Thermodynamical Approach to Predict the Melting Temperature and Stability of an Oligonucleotide Duplex in Solution and on Surface
Ayse Bilge Ozel and Erdogan Gulari, Department of Chemical Engineering, University of Michigan- Ann Arbor, 2300 Hayward St 3074 H H Dow Building, Ann Arbor, MI 48109
Role of Secondary Structure in Polymer Translocation through a Protein Nanopore: a Langevin Dynamics Study
Ajay S. Panwar and Murugappan Muthukumar, Polymer Science and Engineering, University of Massachusetts, 120 Governors Drive, Amherst, MA 01003
DNA Structure within a Virus Particle
Andrew Spakowitz1, Luis Comolli2, Cristina E. Siegerist2, Shelley Grimes3, Paul Jardine3, Kenneth H. Downing2, Dwight Anderson3 and Carlos Bustamante4, (1)Chemical Engineering, Stanford University, Stauffer III - Room 113, 381 North South Mall, Stanford, CA 94305, (2)Subcellular Structure, Life Sciences Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, (3)Diagnostic and Biological Sciences, University of Minnesota, 515 Delaware St SE, 18-246 Moos Tower, Minneapolis, MN 55455, (4)Physics, University of California - Berkeley, 231 Birge Hall, Berkeley, CA 94720-7300
Molecular Dynamics Simulations of Viral Capsid Self-Assembly
Hung D. Nguyen and Charles L. Brooks III, Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, TPC6, La Jolla, CA 92037
Structure and Osmotic Properties of DNA in Lambda Bacteriophages
Zhidong Li and Jianzhong Wu, Chemical and Environmental Engineering, University of California, Riverside, Bourns Hall A242, 900 University Avenue, Riverside, CA 92521
Concluding Remarks

Engineering Sciences and Fundamentals