Preliminary Program subject to change
T8012 (22b) Bionanotechnology for Gene and Drug Delivery
OverviewBionanotechnology uses concepts from chemistry, physics, and molecular biology to identify components and processes for the construction of nanomaterials and nanodevices for health care. This session invites papers that focus on the design and development of nanomaterials and nanodevices for gene and drug delivery. Topics of interest include, but are not limited to: novel methods and compositions to design gene and drug delivery systems at the nanoscale level, and the effects of the sizes of gene and drug delivery systems on gene and drug release kinetics, and pharmacokinetics, cellular uptake, biological transport, and bioefficacy of gene- and drug-carrier complexes.
Primary SponsorTopical 8: Bionanotechnology (T8)
Co-Sponsor(s)Food, Pharmaceutical & Bioengineering Division (15), Pharmaceuticals (See also Topical 2) (15b)

Chair

Tao L. Lowe
Assistant Professor of Surgery, Bioengineering, and Material Sciences and Engineering
Pennsylvania State University
The Milton S. Hershey Medical Center
500 University Dr.
Hershey, PA 17033
Phone Number: (717) 531-8602
Fax Number: (717) 531-4464
Email: tlowe@psu.edu

CoChair

Junghae Suh
Laboratory of Genetics
Salk Institute
10010 North Torrey Pines Road
La Jolla, CA 92037
Phone Number: unknown
Email: jsuh@salk.edu
Folate Conjugated Polymer Micelles Formulated with TPGS for Selective Tumor Targeting
Haizheng Zhao and Lin Yue Lanry Yung, Department of Chemical and Biomolecular Engineering, National University of Singapore, Singapore, Singapore
Cationic B-Cyclodextrin Polymers for Controlled Drug Delivery across the Blood Brain Barrier (Bbb)
Eun Seok Gil, Department of Surgery, Pennsylvania State University, 500 University Drive, Hershey, PA 17033, Tao L. Lowe, Surgery, Bioengineering, and Material Sciences & Engineering, Pennsylvania State University, 500 University Drive, Hershey, PA 17033, Jianshu Li, Department of Chemical Engineering, University of New Brunswick, Fredericton, NB, Canada, Fredericton, NB E3B 5A3, Canada and Huining Xiao, Department of Chemical Engineering, University of New Brunswick, Fredericton, NB E3B 5A3, Canada
Searching for Optimal Properties of Synthetic Gene Vectors Via Simulations of Intracellular Transport Processes
Chinmay Pangarkar, Anh-Tuan Dinh, Theo Theofanous and Samir Mitragotri, Chemical Engineering, University of California, Santa Barbara, Dept. of Chemical Engineering, Santa Barbara, CA 93106
Hydrodynamic Self-Assembly of DNA-Pei Nanoparticles in a Microfluidic System for Gene Delivery
Chee Guan Koh1, Jingjiao Guan1, Zhengzheng Fei1, Yubing Xie1, Bo Yu1, Yihua Loo2, Kam W. Leong2 and L. James Lee3, (1)The Ohio State University, 140 West 19th Ave., Columbus, OH 43210, (2)Department of Biomedical Engineering, Johns Hopkins University, 720 Rutland Avenue / Ross 720, Baltimore, MD 21218, (3)The Ohio State University, 140 West 19th Ave, Columbus, OH 43210
Break
Efficient Nuclear Delivery of Antisense Oligo-Nucleotides by Neutral, Self-Porating Polymersomes
Younghoon Kim1, Manu Tewari2, David Pajeroski2, Shamik Sen2, Williams Jason3, Shashank Sirsi3, Gordon Lutz3 and Dennis E. Discher1, (1)Chemical & Biomolecular Engineering, University of Pennsylvania, 220 South 33rd Street, Room 112 Towne Bldg., Philadelphia, PA 19104-6391, (2)University of Pennsylvania, 220 South 33rd Street, Room 112 Towne Bldg., Philadelphia, PA 19104-6391, (3)Department of Pharmacology & Physiology, Drexel University, Mail Stop 488, 245 N. 15th Street, Philadelphia, PA 19102-1192
Core-Shell Drug Nanoparticles for Therapeutic Delivery
Alisar S. Zahr, Chemical Engineering, The Pennsylvania State Univeristy, 263 MRL, Hastings Rd, University Park, PA 16802 and Michael V. Pishko, Department of Chemical Engineering, The Pennsylvania State University, 104 Fenske Laboratory, University Park, PA 16802-4400
Biodegradable Biphasic Nanocarriers for Multiple Drugs Delivery with Complex Release Profiles in a Controlled Manner
Kyung-Ho Roh, Macromolecular Science and Engineering, University of Michigan, 2300 Hayward Street, Ann Arbor, MI 48109-2136, Sridhar Valluri, Pharmaceutical Engineering, University of Michigan, 2300 Hayward Street, Ann Arbor, MI 48109 and Joerg Lahann, University of Michigan, Dept. of Chemical Engineering, 3074 H.H. Dow Bldg., Ann Arbor, MI 48109-2136

Topical 8: Bionanotechnology