Preliminary Program subject to change
T2004 Process Development Tools for Pharmaceutical Process Development
OverviewThe pharmaceutical engineering lab is endowed with on-line probes that hold the promise of rapid process development without sacrificing process understanding. This session will focus on the application of these lab tools in solving process problems.
Primary SponsorTopical 2: Discover, Development and Delivery of Medicines (T2)
Co-Sponsor(s)Manufacturing (12d)

Chair

Shailendra V. Bordawekar
Research Investigator
Abbott Laboratories
1401 Sheridan Rd
Bldg. R8-3, Dept. R452
North Chicago, IL 60064
Phone Number: 847 935 0212
Email: shailendra.bordawekar@abbott.com

CoChair

Brent Nielsen
Senior Research Investigator
Process R&D
Bristol-Myers Squibb Company
One Squibb Drive
New Brunswick, NJ NJ/08903
Phone Number: 732 227-7971
Email: brient.nielsen@bms.com
Shear-Induced Compaction of Pharmaceutical Formulations
Marcos Llusa1, Bodhisattwa Chaudhuri2, M. Silvina Tomassone1, Mobeen Faqih2, Amit Mehrotra2 and Fernando J. Muzzio2, (1)Chemical and Biochemical Engineering, Rutgers University, 98 Brett Road, Piscataway, NJ 08854, (2)Rutgers University, 98 Brett Road, Piscataway, NJ 08854
A Numerical Investigation of Air Flow during Tablet Compression
Douglas M. Kremer, Pharmaceutical Research and Development, Pfizer, Eastern Point Road, Groton, CT 06340
Combined Experimental and Modeling Study of a Kinetic Resolution
John W. Shabaker, Srinivas Tummala, Erqing Tang, Olav Lyngberg and Lindsay Hobson, Bristol-Myers Squibb Company, One Squibb Drive, New Brunswick, NJ 08903
On-Line Ftir Measurements for the Pilot-Plant Scale-up of a Borane Reduction Process
Camille O. Anderson, George Zhou and Brian Phenix, Global Pharmaceutical Commercialization, Merck & Co., Inc., P.O. Box 2000, Rahway, NJ 07065
Development of a Generic Process Model for Dynamic Simulation of Protein Downstream Processes
Constantin Frerick, Peter Kreis and Andrzej Górak, Dortmund University, Chair of Fluid Separation Processes, Dortmund, 44221, Germany
Catalyst Trap Microreactor for Pharmaceutical Hydrogenation
Shaun M. McGovern1, G. Harish2 and Ronald S. Besser2, (1)Chemical, Biomedical and Materials Engineering, Stevens Institute of Technology, Castle Point on Hudson, Hoboken, NJ 07030, (2)Chemical, Biomedical, and Materials Engineering, Stevens Institute of Technology, Castle Point on Hudson, Hoboken, NJ 07030
Ion Exchange Process Development with Pat
James Marek, Shekhar K. Viswanath and John Tolle, Process R&D, Abbott Labs, 1401 Sheridan Road, R13-3, North Chicago, IL 60064

Topical 2: Discovery, Development and Delivery of Medicines