Optimization of in Vitro Erythropoieis for Genotoxicity Testing
Joe Shuga1, Jing Zhang2, Leona Samson3, Harvey Lodish3 and Linda Griffith3, (1)Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139, (2)Whitehead Institute for Biomedical Research, Cambridge, MA, (3)Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139 |
Model-Based Optimisation of Mammalian Cell Cultures: a Case Study for Optimising Glucose and Glutamine Fed-Batch Profiles for CHO-IFNγ Cell Line
Carolyn M. C. Lam1, Danny C. F. Wong2, Miranda G. S. Yap2, Efstratios N. Pistikopoulos3 and Athanasios Mantalaris3, (1)Chemical Engineering Department, Imperial College London, South Kensington campus, London, SW7 2AZ, United Kingdom, (2)Bioprocessing Technology Institute, Agency for Science and Technology Research (A*STAR), 20 Biopolis Way, #06-01, Centros, Singapore, 138668, Singapore, (3)Chemical Engineering, Imperial College London, South Kensington campus, London, SW7 2AZ, United Kingdom |
Liver Endothelial Cells Promote Ldl-R Expression and the Uptake of Hcv-like Particles in Primary Hepatocytes
Yaakov Nahmias, Massachusetts General Hospital, Harvard Medical School, 51 Blossom street, Boston, MA 02114, Monica Casali, Center for Engineering in Medicine, 51 Blossom Street, Boston, MA 02114, Laurent Barbe, Shriners Burns Hospital / Massachusetts General Hospital / Harvard Medical School, 51 Blossom street, Boston, MA 02114, Francois Berthiaume, Massachusetts General Hospital, Harvard Medical School, Cambridge, MA 02138 and Martin L. Yarmush, Massachusetts General Hospital, Harvard Medical School, 51 Blossom St, Boston, MA 02114 |
Insights into Hepatic Metabolism from Flux Balance and Pathway Analyses
Hong Yang1, Charles M. Roth2 and Marianthi Ierapetritou1, (1)Department of Chemical and Biochemical Engineering, Rutgers, the State University of New Jersey, 98 Brett Road, Piscataway, NJ 08854, (2)Department of Chemical and Biochemical Engineering,Department of Biomedical Engineering, Rutgers, the State University of New Jersey, 98 Brett Road, Piscataway, NJ 08854 |
Engineering Cancer-Specific Cis-Acting Intronic Regulators of Alternative Splicing as Novel Tools for Disease Detection and Treatment
Stephanie Culler, Chemical Engineering, California Institute of Technology, 1200 E. California Blvd, MC 210-41, Pasadena, CA 91125 and Christina Smolke, Chemistry & Chemical Engineering, California Institute of Technology, 1200 E. California Blvd, MC 210-41, Pasadena, CA 91125 |
Effects of Igf-1 Modified Ehd Networks on Myoblastic Cell Proliferation
Erin E. Falco, Department of Chemical and Biomolecular Engineering, University of Maryland, College Park, MD 20742, Eve M. Rubinstein, University of Maryland, College Park, MD 20742, J. Scott Roth, Department of General Surgery, University of Maryland Medical School, Baltimore, MD 21201 and John P. Fisher, University of Maryland, Department of Chemical Engineering, 2113 Chemical & Nuclear Engineering Bldg., College Park, MD 20742-2111 |
A Chemically Inducible Cucumber Mosaic Virus Amplicon Expression System for Production of Recombinant Human Therapeutics in Transgenic Plant Cell Cultures
Ting-Kuo Huang1, Michael A. Plesha1, Bryce W. Falk2, Abhaya M. Dandekar3 and Karen A. McDonald1, (1)Department of Chemical Engineering and Materials Science, University of California, Davis, 1 Shields Ave., Davis, CA 95616, (2)Department of Plant Pathology, University of California, Davis, 1 Shields Ave., Davis, CA 95616, (3)Department of Plant Sciences, University of California, Davis, 1 Shields Ave., Davis, CA 95616 |
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