Preliminary Program subject to change
T2012 Separations in Biopharmaceutical Downstream Processing II (Including Pat Applications)
OverviewThis is a continuation of Part I (session T2013), including PAT applications in biopharmaceutical manufacturing, process development and research and development.
Primary SponsorTopical 2: Discover, Development and Delivery of Medicines (T2)

Chair

Min Jiang
Group Leader
Manufacturing Science and Technology, Global Pharmaceutical Operations
Abbott Laboratories
Dept. 045B NCR13-4
1401 N. Sheridan Road
North Chicago, IL 60064
Phone Number: 847-935-3554
Email: min.jiang@abbott.com

CoChair

John F. Peragine
Principal Technical Investigator
Bristol-Myers Squibb Company
1 Squibb Drive
Bldg. 137 rm 389
New Brunswick, NJ 08903
Phone Number: 732 227-5688
Fax Number: 732 227-3892
Email: john.peragine@bms.com
Utilizing on-Line Hplc to Enable Process Monitoring, Automation, and Control of Downstream Unit Operations in a Biopharmaceutical Process
Joseph J. Zajac1, Jimmy D. Engle1, Jerry L. Shrake1 and Rick E. Cooley2, (1)Process Analytical Technology, Eli Lilly and Company, Corporate Center, Indianapolis, IN 46285, (2)Dionex Corporation and Eli Lilly and Company (retired), 2239 Foxcliff Estates North, Martinsville, IN 46151
Instantaneous Microbial Detector for Pat Application
J. P. Jiang, BioVigilant, 2015 W. Ruthrauff Road, Suite 153, Tucson, AZ 85705
Affinity Enhanced Gel Permeation Chromatography of Proteins upon Modification with Multi-Ligand Affinity Carriers
Javier Garcia, University of Arizona, Chemical and Environmental Engineering Dept., Harshbarger Bldg, Room 108, Tucson, AZ 85721 and Roberto Guzman, University of Arizona, Chemical and Environmental Engineering Dept., Harshbarger Bldg, Room 146A, Tucson, AZ 85721
Purification of Factor V Leiden Molecule from Homozygous Patient's Plasma for Biosensor Development
Samin Rezania1, Yongjie Ren2 and Kyung A. Kang2, (1)University of Louisville, 106 EH Dept. of Chem. Eng., University of Louisville, Louisville, KY 40292, (2)Chemical Engineering, University of Louisville, 106 EH Dept. of Chem. Eng., University of Louisville, Louisville, KY 40292
Preparative-Scale Dynamic Field Gradient Focusing: Proof of Concept
Noah I. Tracy and Cornelius F. Ivory, Chemical Engineering, Washington State University, PO Box 642710, Pullman, WA 99164
Manipulation of the Adsorption of Factor II, a Protein C Homologue, Using Imidazole during Immobilized Metal Affinity Chromatography Purification of Protein C from Cohn Fraction IV-1
James J. Lee1, Duane F. Bruley2 and Kyung A. Kang1, (1)Chemical Engineering, University of Louisville, Eastern Parkway, Louisville, KY 40292, (2)Chemical and Biochemical Engineering, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250

Topical 2: Discovery, Development and Delivery of Medicines