Comparison of a New Continuous Chromatographic Solvent Gradient Process for Bioseparations with Conventional Processes
Guido Stroehlein, Lars Aumann, Abhijit Tarafder, Thomas Mueller-Spaeth and Massimo Morbidelli, Institute for Chemical- and Bioengineering, ETH Zurich, Wolfgang-Pauli-Str. 10, HCI-F-128, Zurich, 8093, Switzerland |
Scale down Model Demonstrates High Prodcut Throughputs with Disposable Anion Exchange Chromatography
Jeff D. Mora1, Uwe Gottschalk1, Oscar Reif2, Joe Zhou3, Felix Solamo3, Shinta Dermawan3, Tony Hong3 and Tim Tressel3, (1)Biotechnology, Sartorius, 131 Heartland Blvd, Edgewood, NY 11717, (2)Research & Development, Sartorius, 131 Heartland Blvd, Edgewood, NY 11717, (3)Purification Process Development, Amgen, One Amgen Center Drive, 30W-2-A, Thousand Oaks, CA 34065 |
Downstream Separation and Scale-up Challenges for E.Coli-Derived Biopharmaceuticals – an Industrial Study on Development of an Antibody Fragment (Fab) Process
Abdul Wajid, Technical Development, XOMA(US) LLC, 2910 Seventh Street, Berkeley, CA 94710 and Daljit Narindray, Technical Development, XOMA(US) LLC, 2910 Seventh Street, Berkeley, CA 94710 |
A Toolbox for Efficient Release and Recovery of Therapeutic Proteins from the Periplasm of Pseudomonas Fluorescens
Anant Patkar, Subrata Sen, Mike Chappell, Yuk Chun Chiu, Jeff Allen and Jefry Shields, Core Biotechnology R&D, The Dow Chemical Company, 5501 Oberlin Dr., San Diego, CA 92121 |
Diverse Transgenic Plant Hosts Challenge Downstream Process Development
Zivko L. Nikolov, Susan L. Woodard, Lisa R. Wilken, Steve G. White and Georgia Barros, Biological and Agricultural Engineering, Texas A&M University, 2117 TAMU, College Station, TX 77845 |
High Throughput Protein Purification Using Negative Mode Hydrophobic Interaction Chromatography
Jennifer McNay, Kenneth Audo and Kevin Bailey, Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591 |
Separation of Pharmaceutical Process-Related Impurities by an Organic Solvent Nanofiltration Membrane Cascade
Justin Chun-Te Lin, Ludmila G. Peeva and Andrew G. Livingston, Department of Chemical Engineering and Chemical Technology, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom |
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