Preliminary Program subject to change
02B01 Crystallization of Pharmaceutical and Biological Molecules - I
OverviewPapers addressing fundamental as well as applied studies in the area of pharmaceutical and biological molecule crystallization are welcomed. It is anticipated that several papers will focus on bio-macromolecular crystallization (proteins, DNA, RNA etc). In addition, studies focused on small or intermediate molecular weight molecules are welcome provided such studies are relevant to biology or pharmaceutics. Industrial case studies or "war stories" are encouraged. The session hopes to provide a balance of applied and fundamental studies
Primary SponsorCrystallization and Evaporation (02b)

Chair

Donald J. Kirwan
Chemical Engineering
University of Virginia
Department of Chemical Engineering
Charlottesville, VA 22904-4741
Phone Number: 434-924-6278
Fax Number: 434-982-2658
Email: djk@virginia.edu

CoChair

Shekhar K. Viswanath
Process Engineering Group Leader
Abbott Labs
1401 Sheridan Road, R13-3
North Chicago, IL 60064
Phone Number: 847-935-8660
Fax Number: 847-938-5932
Email: shekhar.viswanath@abbott.com
Producing Small Crystals of a Pharmaceutical Compound by a Continuous Polymorph Transformation Process
Bing Shiou Yang, Chenkou Wei and San Kiang, Bristol-Myers Squibb Company, One Squibb Drive, New Brunswick, NJ 08903
Rapid Expansion of Supercritical Solution with Solid Cosolvent (Ress-Sc) Process for Pharmaceutical Nanoparticles Formation
Ram B. Gupta and Ranjit Thakur, Chemical Engineering, Auburn University, 0322 Haley Center, Auburn, AL 36849-5127
Characterizing Intermolecular Interactions from Self-Diffusion Coefficients to Locate Conditions for Spherical Crystallization
Guangwen He1, Reginald B. H. Tan2, Paul J. A. Kenis3 and Charles F. Zukoski3, (1)Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, 600 S. Mathews Ave., Urbana, IL 61801, (2)Department of Chemical & Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore, 117576, (3)Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign, 600 S. Mathews Ave., Urbana, IL 61801
Concomitant Polymorphism in Industrial Precipitation Processes
Pieter J. Jansens, J.H. ter Horst and H.J.M. Kramer, P&E, Separation Technology, Delft University of Technology, Leeghwaterstraat 44, Delft, 2628 CA, Netherlands
Making Co-Crystals – the Utility of Ternary Phase Diagrams
Renato A. Chiarella1, Roger J. Davey2 and Matthew L. Peterson1, (1)TransForm Pharmaceuticals, 29 Hartwell Av, Lexington, MA 02139, (2)University of Manchester, PO Box 88, Manchester, M60 1QD, United Kingdom
High Throughput Nanoliter Screening and Morphological Control of Protein Crystals Via Precipitant Gradients
Goher Mahmud, Stoyan K. Smoukov, Yuriy Chegel and Bartosz A. Grzybowski, Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Ave., Tech E-136, Evanston, IL 60208

Separations Division