| Increasing demand for recombinant proteins has focused research on techniques for improving protein expression and controlling post-translational processing. We invite papers on all aspects of protein expression including novel cell systems, expression vectors, and culture conditions. Submissions dealing with post-translational processing including glycosylation, editing and secretion are also invited. Papers may deal with any cell type including bacteria, yeast, mammalian, insect and plant cell cultures. |
Exceptional Total and Functional Yields of the Human Adenosine a2a Receptor Expressed in the Yeast Saccharomyces Cerevisiae
Michelle O'Malley1, Ronald Niebauer2 and Anne Skaja Robinson1, (1)University of Delaware, 259 Colburn Laboratory, Department of Chemical Engineering, Newark, DE 19716, (2)*current address, Laboratory of Molecular Biology, National Institutes of Health, Bethesda, MD 20892 |
Enabling Biosynthesis of Complex Proteins in Bacteria Via Ribosome Reprogramming
Lydia M. Contreras, Cornell University, Chemical and Biomolecular Engineering, Ithaca, NY 14853 and Matthew P. DeLisa, School of Chemical and Biomolecular Engineering, Cornell University, 120 Olin Hall, Ithaca, NY 14853-5201 |
Humanization and Structural Studies to Tailor the Efficiency of Pertussis Toxin (Pt) Neutralizing Antibodies
Kavita Ramalingam Iyer and Jennifer A. Maynard, Chemical Engineering and Materials Science, University of Minnesota, 151, Amundson hall,, 421 Washington Avenue SE, Minneapolis, MN 55455 |
Cellular and Protein Engineering Approaches for Increasing Human Brain-Derived Neurotrophic Factor Production in Yeast
Michael L. Burns and Eric Shusta, University of Wisconsin, 1415 Engineering Drive, Madison, WI 53715 |
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Engineering Membrane Protein Biogenesis
A. James Link1, Nandini S. Aiyappan2 and George Georgiou1, (1)Chemical Engineering, University of Texas at Austin, 1 University Station C0400, Austin, TX 78712, (2)Institute for Cellular and Molecular Biology, University of Texas at Austin, 1 University Station C0400, Austin, TX 78712 |
Directed Evolution of a G-Protein Coupled Receptor
Casim A. Sarkar, Departments of Bioengineering and Chemical & Biomolecular Engineering, University of Pennsylvania, 305 Hayden Hall, 3320 Smith Walk, Philadelphia, PA 19104-6392 and Andreas Plueckthun, University of Zurich, Zurich, Switzerland |
Cell-Free Protein Synthesis of Complex Proteins Containing Unnatural Amino Acids
Aaron R. Goerke, Jessica J. Wuu and James R. Swartz, Department of Chemical Engineering, Stanford University, Stanford, CA 94305-5025 |
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