Preliminary Program subject to change
15D14 Drug Delivery (II)
OverviewThis session highlights recent research efforts in the broad area of design, characterization (in vitro and in vivo), and development of drug delivery systems with multi-functional properties for targeted and sustained drug delivery. Topics of interest include, but are not limited to: Effects of chemical structure and/or physical properties of drug delivery systems on loading efficiency and release kinetics; functionalizing drug carriers with moieties for specific targeting; blood circulation time and biodistribution of drug-carrier complexes after systemic injection; in vitro and in vivo studies of cellular uptake.
Primary SponsorEngineering Fundamentals in Life Science (15d)

Chair

Efrosini Kokkoli
Department of Chemical Engineering and Materials Science
University of Minnesota
Minneapolis, MN 55455
Phone Number: 612-626-1185
Fax Number: 612-626-7246
Email: kokkoli@cems.umn.edu

CoChair

Stavroula Sofou
Polytechnic University
Department: Chemical and Biological Sciences and Engineering
Room RH 729A, 6 MetroTech Center
Brooklyn, NY 11201
Phone Number: (718) 260-3863
Fax Number: (718) 260-3125
Email: ssofou@duke.poly.edu
The Interplay of Drug, Polymer, and Solvent Properties on the Release Characterisitics of Membrane-Based Systems
Anthony J. McHugh, Decheng Ma and Michael Marsh, Chemical Engineering, Lehigh University, 111 Research Drive, Bethlehem, PA 18015
Targeting the Breast Cancer Microenvironment Using Interleukin-12 Conjugated Pamam Dendrimers
Kelsey Yee1, Erin Rieke1, Stuart Helfand2 and Christine J. Kelly1, (1)Chemical Engineering, Oregon State University, 103 Gleeson Hall, Corvallis, OR 97331, (2)College of Veterinary Medicine, Clinical Sciences, Oregon State University, 200 Magruder Hall, Corvallis, OR 97331
Nanoparticles for Targeted Delivery to Prostate Cancer Cells
Aleksandar F. Radovic-Moreno1, Benjamin A. Teply2, Jason Fuller2, Frank Gu2, Etgar Levy-Nissenbaum2, Robert Langer3 and Omid C. Farokhzad4, (1)Harvard-MIT Division of Health Sciences & Technology, Massachusetts Institute of Technology, 45 Carleton St, E25-342, Cambridge, MA 02142, (2)Department of Chemical Engineering, Massachusetts Institute of Technology, 45 Carleton St, E25-342, Cambridge, MA 02142, (3)Chemical Engineering and Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Room E25-342, Cambridge, MA 02139, (4)Department of Anesthesiology, Harvard Medical School, 75 Francis St, Boston, MA 02155
Recognition of the Size of Polymer Drug Carriers by Macrophages
Julie Champion and Samir Mitragotri, Chemical Engineering, University of California Santa Barbara, Engineering II Rm 3229, Santa Barbara, CA 93106
Break
Oral Delivery of Insulin Bioconjugates Using Intelligent Complexation Hydrogels
Justin P. Shofner, Nikhil J. Kavimandan and Nicholas A. Peppas, Department of Chemical Engineering, University of Texas at Austin, 1 University Station C0400, Austin, TX 78712
Validation of a Model Predicting the Influence of Cyclodextrins on Oral Bioavailability: Comparison with in Vitro and in Vivo Data
Ece D. Gamsiz1, Avinash G. Thombre2, Lee A. Miller3 and Rebecca L. Carrier1, (1)Department of Chemical Engineering, Northeastern University, 342 Snell Engineering Center, Boston, MA 02115, (2)Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340, (3)Pfizer Global Research and Development, Ann Arbor, MI
A Release Rate Study for Controlled Drug Delivery Using Niosomes
Kristina O. Dearborn, Ryan G. Toomey, Michael D. VanAuker and Norma Alcantar, Chemical Engineering, University of South Florida, 4202 E. Fowler Ave., Tampa, FL 33620

Food, Pharmaceutical & Bioengineering Division