Understanding the Reaction Mechanism of Protein Splicing in Order to Gain Insights for the Engineering of Inteins
Brian Pereira1, Philip Shemella2, Patrick Van Roey3, Marlene Belfort3, Victoria Derbyshire3, Saroj Nayak2, Georges Belfort1 and Shekhar Garde1, (1)Chemical and Biological Engineering, Rensselaer Polytechnic Institute, 110 8th ST, Troy, NY 12180, (2)Physics, Applied Physics, and Astronomy, Rensselaer Polytechnic Institute, 110 8th ST, Troy, NY 12180, (3)Wadsworth Center, New York State Department of Health, and School of Public Health, University at Albany, Albany, NY 12201 |
Antibody Affinity Maturation Using Computational Protein Design
Shaun M. Lippow, Chemical Engineering, MIT, 32-211, Cambridge, MA 02139, Bruce Tidor, Biological Engineering; Electrical Engineering & Computer Science, MIT, Cambridge, MA 02139 and K. Dane Wittrup, Chemical Engineering; Biological Engineering, MIT, Cambridge, MA 02139 |
Computation-Guided Design of Arac Regulatory Protein Effector Specificity
Hossein Fazelinia, Department of Chemical Engineering, The Pennsylvania State University, State College, PA 16802, Patrick C. Cirino, Penn State University, 120 Fenske Lab, University Park, PA 16802 and Costas D. Maranas, Department of Chemical Engineering, 112 Fenske Laboratory, University Park, PA 16802 |
Application of the Consensus Concept for Increased Thermostability of Enzymes
Eduardo Vazquez-Figueroa1, Javier Chaparro-Riggers1, Karen M. Polizzi1 and Andreas S. Bommarius2, (1)School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Dr, Atlanta, GA 30332, (2)Chemical & Biomolecular Engineering, Georgia Tech, 315 Ferst Dr, Atlanta, GA 30332-0363 |
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Bioinformatics-Mediated Rational Approaches to Protein Engineering for Increased Stability
Philippa J. Reeder1, Christopher Bystroff2 and Jonathan S. Dordick1, (1)Chemical and Biological Engineering, Rensselaer Polytechnic Institute, 110 8th St, Troy, NY 12180, (2)Biology, Rensselaer Polytechnic Institute, 110 8th St, Troy, NY 12180 |
Engineering Transcription Factors with Novel DNA-Binding Specificity Using Comparative Genomics
Tasha Desai, Chemical and Biomolecular Engineering, University of Illinois, 600 South Matthews Ave., 211 Roger Adams Laboratory, Box C-3, Urbana, IL 61801 and Christopher V. Rao, Department of Chemical and Biomolecular Engineering, University of Illinois, 600 South Matthews Ave., 211 Roger Adams Laboratory, Box C-3, Urbana, IL 61801 |
Genetic Selection of Stable Single-Chain Immunotherapeutics in the Cytoplasm of Escherichia Coli
Adam C. Fisher, Cornell University, 304 Olin Hall, Ithaca, NY 14853 and Matthew P. DeLisa, School of Chemical and Biomolecular Engineering, Cornell University, 120 Olin Hall, Ithaca, NY 14853-5201 |
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