| Separations are a critical unit operation in any bioprocess. Biological metabolites are typically produced in relatively low amounts and thus concentration and purification can add significant cost to the overall processes. Separation of biological molecules and effluents often require special considerations not generally applicable to nonbiological separations. The focus of this session is to highlight the latest theoretical and experimental advances in bioseparations that promise to reduce costs and improve separation efficiency. Topics to be covered will include, but are not limited to: (1) crystallization and evaporation, (2) membrane-based bioseparations, (3) adsorption and ion exchange, (4) extraction, and (5) simulated moving bed chromatography. |
Simple and Economical Purification of Recombinant Proteins by Self-Cleaving Aggregation Tags
David W. Wood, Haihua Chu, Courtney Mee and Mahmoud Reza Banki, Chemical Engineering, Princeton University, A213 EQUAD, Princeton, NJ 08544 |
Molecularly Imprinted Polymeric Microparticles for Bio-Analytical Applications
Olympia Kotrotsiou, Aristotle University of Thessaloniki & Chemical Process Engineering Research Institute, P.O. Box 472, Thessaloniki, 54124, Greece and Costas Kiparissides, Department of Chemical Engineering, Aristotle University of Thessaloniki & Chemical Process Engineering Research Institute, P.O. Box 472, Thessaloniki, 54124, Greece |
A Rational Method to Improve Bioseparation Via Proteomics
Robert R. Beitle1, Rajaramesh Varakala1, Ryan Haley1, Ralph Henry2 and Mohammad Ataai3, (1)Ralph E. Martin Department of Chemical Engineering, University of Arkansas, 3202 Bell Engineering Center, Fayetteville, AR 72701, (2)Biological Science, University of Arkansas, 3202 Bell Engineering Center, Fayetteville, AR 72701, (3)Chemical and Petroleum Engineering, University of Pittsburgh, 300 Technology Drive, Pittsburgh, PA 15219 |
A Proteomics Approach to Evaluate Expression Host and Downstream Recovery Compatibility: Analysis of Maize and Ion Exchange Chromatography
Li Xu and Charles E. Glatz, Chemical and Biological Engineering, Iowa State University, Ames, IA 50011 |
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Purification of Biomolecules by Multicolumn Countercurrent Solvent Gradient Chromatography (Mcsgp)
Thomas Müller-Späth, Lars Aumann, Guido Ströhlein, Abhijit Tarafder and Massimo Morbidelli, Institute for Chemical- and Bioengineering, ETH Zurich, Wolfgang-Pauli-Str. 10, HCI-F-128, Zurich, 8093, Switzerland |
Purification of E. Coli Inner Membrane Vesicles by Biotin-Streptavidin Interaction
Norman T. Hovijitra, Chemical Engineering, Stanford University, Mountain View, CA 94305 and James R. Swartz, Chemical Engineering, Stanford University, 380 Roth Way, MC 5025, Stanford, CA 94305 |
Osmotic Second Virial Coefficient as a Useful Tool to Optimize Self Assembly of Virus-like Particles
Yap Pang Chuan, Centre for Biomolecular Engineering, Department of Chemical Engineering, University of Queensland, University of Queensland, Brisbane, Queensland 4072, Australia, brisbane, Australia and Anton P. J. Middelberg, Centre for Biomolecular Engineering, University of Queensland, Brisbane, Queensland 4072, Australia, Brisbane, Australia |
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