| This session will highlight engineering approaches to problems in cancer, cardiovascular and other diseases. Emphasis will be on studies of transport, cell and tissue mechanics, heat transfer, and kinetics applied specifically to the areas of tumor biology, metastasis, and the circulation. Topics may span length-scales from molecular to organismal physiology, involving computational and/or experimental methods. Sample topics include: - angiogenesis - atherosclerosis - cancer cell adhesion and migration - cancer cell signaling - intracellular metabolism - diabetes - gene therapies – novel therapeutic strategies - ischemia / reperfusion injury - models of tumor development - sickle cell disease - thrombosis/fibrinolysis - tumor pharmacokinetics and drug delivery. |
Scaffold Mesh Size and Mechanical Properties and Their Effects on Tevg Outcome
Dany Munoz-Pinto, Chemical Engineering, Texas A&M University, 3122 TAMU, College Station, TX 77843-3122 and Mariah Hahn, Chemical Engineering, Texas A&M University, 3122 TAMU, College Station, TX 77843 |
Inter-Domain Non-Covalent Interactions Stabilize the Solution Structure of Human Von Willebrand Factor
Indrajeet Singh1, Harish Shankaran1, Mark E Beauharnois1, Zhihua Xiao1, Paschalis Alexandridis1 and Sriram Neelamegham2, (1)Chemical And Biological Engineering, State University of New York at Buffalo, 303 Furnas Hall, North Campus, AMHERST, NY 14226, (2)Chemical And Biological Engineering, State University of New York at Buffalo, 303 Furnas Hall, North Campus, Amherst, NY 14226 |
Characterization of Peptides Isolated from Bacterial Display Libraries Binding to Tumor Cell Surface Receptors
Karen Y. Dane, Yimin Zhu and Patrick S. Daugherty, Chemical Engineering, UCSB, Engineering II, Room 3357, Santa Barbara, CA 93106-5080 |
Targeting L-Methioninase to the Vasculature of Tumors
Naveen R. Palwai1, Peter S. McFetridge1, J. Thomas Pento2 and Roger G. Harrison1, (1)School of Chemical, Biological and Materials Engineering, University of Oklahoma, 100 E. Boyd, Room T335, Norman, OK 73019, (2)Department of Pharmaceutical Sciences, University of Oklahoma, Health Sciences Center, 1110 N. Stonewall, Oklahoma City, OK 73117 |
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Dendrimer-Based Nanodevices for Targeted Cancer Therapy Based on Mechanistic Understanding of Device Performance
Sezen Gurdag, Wayne State University, Detroit, MI 48202, Rangaramanujam M. Kannan, Wayne State University, 1121 Engineering, 5050 Anthony Wayne Drive, Detroit, MI 48202, Sarah Staples, Karmanos Cancer Institute, Detroit, MI 48202 and Larry Matherly, Cancer Biology, Karmanos Cancer Institute, Detroit, MI 48202 |
The Role of Mesenchymal Bone Marrow-Derived Cells in Tumor Formation
Michelle R. Dawson, Dan G. Duda and Rakesh K. Jain, Department of Radiation Oncology, Edwin L. Steele Laboratory, Massachusetts General Hospital, Harvard Medical School, 100 Blossom Street, Cox 7, Boston, MA 02114 |
Influence of Toxicity Effects on Model-Based Docetaxel Treatment Design
Jeffry A. Florian Jr., Chemical and Petroleum Engineering, University of Pittsburgh, 1272 Benedum Hall, Pittsburgh, PA 15261 and Robert S. Parker, Chemical Engineering, University of Pittsburgh, 1272 Benedum Hall, Pittsburgh, PA 15261 |
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