| We seek presentations that utilize experimental methods, computational modeling, and integrated experimental and computational approaches for the analysis of intracellular processes, in the context of biomedical systems. Topics of interest include, but are not limited to: binding and molecular interactions, gene and protein networks, crosstalk between signaling pathways, signaling pathway dynamics, and intracellular trafficking, and novel approaches for monitoring intracellular processes. Multi-scale approaches involving measurement and regulation across gene, protein, and metabolic systems are particularly encouraged. |
Inferring Equilibrium Protein Binding Using Fret Imaging Data
Khamir Mehta1, Adam Hoppe2, Peter J. Woolf1 and Jennifer J. Linderman1, (1)Chemical Engineering, University of Michigan, Ann Arbor, MI 48109-2136, (2)Department of Microbiology and Immunology, University of Michigan, 1150 W. Med. Ctr. Dr., Med. Sci. II, RM 5631, Ann Arbor, MI 48109-0620 |
The Effects of Ppar Modulation on Cox-2-Depedent Inflammation and Apoptosis in Shear-Activated Chondrocytes: a Role in Arthritis
Zachary Healy, Chemical & Biomolecular Engineering, Johns Hopkins University, 3400 N. Charles Street, Maryland Hall Room 223, Baltimore, MD 21218, Norman Lee, Molecular Biololgy and Functional Genomics, The Institute for Genomic Research, 9700 Medical Center Drive, Rockville, MD 21085, Paul Talalay, Pharmacology, Director of the Laboratory for Molecular Sciences, Johns Hopkins University - School of Medicine, 725 N Wolfe Street, Baltimore, MD 21205 and Konstantinos Konstantopoulos, Johns Hopkins University, 221 Maryland Hall, 3400 North Charles Street, Baltimore, MD 21218 |
Towards Quantitative Understanding of Mass Transfer in the Endocytic Pathway
Chinmay Pangarkar, Anh-Tuan Dinh and Samir Mitragotri, Chemical Engineering, University of California, Santa Barbara, Dept. of Chemical Engineering, Santa Barbara, CA 93106 |
Apoptosis of Human Hepatocellular Carcinoma Cell Is Regulated by Palmitic Acid through the Signal Transduction from Pkr to Bcl-2
Xuerui Yang, Department of Chemical Engineering and Materials Science, Michigan State University, 2527 Engineering Building, East Lansing, MI 48824 and Christina Chan, Chemical Engineering and Material Science, Michigan State University, 2527 Engineering Building, East Lansing, MI 48824 |
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Involvement of Jnk in Cellular Trafficking of Adherens Junction Proteins E-Cadherin and Β-Catenin: Implication to Cell-Cell Adhesion
Piyush Koria, SUNY at Buffalo, 916 Furnas Hall, Amherst, NY 14260 and Stelios T. Andreadis, SUNY at Buffalo, 908 Furnas Hall, Amherst, NY 14260 |
Manipulation and Kinetic Analysis of Crosstalk between Pi 3-Kinase/Akt and Ras/Erk Signal Transduction Pathways
Chun-Chao Wang1, Michael Monine2 and Jason Haugh1, (1)Chemical & Biomolecular Engineering, North Carolina State University, Raleigh, NC 27695, (2)Chemical & Biomolecular Engineering, North Carolina State University, Raleigh, NC 27695-7905 |
Analyzing the Stress Response Pathway in Saccharomyces Cerevisiae
Ping Xu1, David Raden1, Scott Hildebrandt2, Francis J. Doyle III2 and Anne Skaja Robinson1, (1)University of Delaware, 259 Colburn Laboratory, Department of Chemical Engineering, Newark, DE 19716, (2)Chemical Engineering, University of California, Santa Barbara, Santa Barbara, CA 93106 |
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