Preliminary Program subject to change
15D03 Gene Therapy and Delivery (I)
OverviewThis session will be devoted to the development of improved methods of gene transfer using both viral and non-viral approaches. Topics of interest include, but not limited to design of novel formulations for improved gene delivery, determination of rate-limiting steps of gene transfer, targeting of gene transfer vectors, methods for production and purification of viral and non-viral vectors and gene transfer to stem cells for tissue engineering applications. This session has been very well attended in previous years.
Primary SponsorEngineering Fundamentals in Life Science (15d)

Chair

Stelios T. Andreadis
Professor
Chemical and Biological Engineering
SUNY-Buffalo
303 Furnas Hall
Buffalo, NY 14260
Phone Number: 716-645-2911
Email: sandread@eng.buffalo.edu

CoChair

Joseph M. Le Doux
Associate Professor
Biomedical Engineering
Georgia Institute of Technology
Atlanta, GA 30332
Phone Number: 404-385-0632
Email: joe.ledoux@bme.gatech.edu
Relationships between Molecular Properties of Polymer-Oligonucleotide Complexes and Cellular Antisense Activity
Sumati Sundaram1, Li Kim Lee1, Mark E Hwang2 and Charles M. Roth3, (1)Chemical and Biochemical Engineering, Rutgers University, 98 Brett Road, Piscataway, NJ 08854, (2)Biomedical Engineering, Rutgers University, 98 Brett Road, Piscataway, NJ 08854, (3)Chem And Biochem Eng/Biomedical Engineering, Rutgers University, Piscataway, NJ 08854
Engineering Adeno-Associated Viral Vectors with Novel Cell Tropisms
James T. Koerber, UC Berkeley, 201 Gilman Hall, Berkeley, CA 94720 and David V. Schaffer, Department of Chemical Engineering and Helen Wills Neuroscience Institute, University of California Berkeley, 201 Gilman Hall, Berkeley, CA 94720
Engineering Cell Lines for the Production of Highly Replication Defective Herpes Simplex Virus Type 1 Vectors
Kyle G. Grant, Chemical Engineering, University of Pittsburgh, 100 Technology Drive Room 526, Pittsburgh, PA 15219, David M. Krisky, Molecular Genetics and Biochemistry, University of Pittsburgh, 200 Lothrop Street BST E1240, Pittsburgh, PA 15261, Mohammad Ataai, Department of Chemical and Petroleum Engineering, University of Pittsburgh, Pittsburgh, PA 15261 and Joeseph Glorioso III, Molecular Genetics and Biochemistry Department, University of Pittsburgh, Pittsburgh, PA 15261
Flow-Enhanced Measurement of Virus Infectivity
Ying Zhu, Chemical and Biological Engineering, University of Wisconsin-Madison, 3735 Engineering Hall, 1415 Engineering Drive, Madison, WI 53706 and John Yin, Chemical and Biological Engineering, University of Wisconsin-Madison, 3633 Engineering Hall, 1415 Engineering Drive, Madison, WI 53706
Break
Linear-Dendritic Hybrid Polymers for Targeted Gene Delivery to Antigen-Presenting Cells in Vivo
Kris C. Wood1, Robert Langer2 and Paula T. Hammond1, (1)Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Room 66-525, Cambridge, MA 02139, (2)Massachusetts Institute of Technology, 77 Massachusetts Avenue, Room E25-342, Cambridge, MA 02139
Controllable Concentration Gradients by Spatially Patterned Gene Delivery
Tiffany Houchin-Ray and Lonnie D. Shea, Department of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Road, Tech E136, Evanston, IL 60208
Rapid Modification of Retrovirus Surfaces for Targeted Gene Delivery
Nimisha Gupta, Biomedical Engineering, Georgia Institute of Technology, 315 Ferst Drive NE, Atlanta, GA 30332 and Joseph M. Le Doux, Biomedical Engineering, Georgia Institute of Technology, 315 Ferst Drive, Atlanta, GA 30332

Food, Pharmaceutical & Bioengineering Division