| This session will highlight engineering approaches to problems in cancer, cardiovascular and other diseases. Emphasis will be on studies of transport, cell and tissue mechanics, heat transfer, and kinetics applied specifically to the areas of tumor biology, metastasis, and the circulation. Topics may span length-scales from molecular to organismal physiology, involving computational and/or experimental methods. Sample topics include: - angiogenesis - atherosclerosis - cancer cell adhesion and migration - cancer cell signaling - intracellular metabolism - diabetes - gene therapies – novel therapeutic strategies - ischemia / reperfusion injury - models of tumor development - sickle cell disease - thrombosis/fibrinolysis - tumor pharmacokinetics and drug delivery. |
Modeling Delivery of Supplemental Nitric Oxide in Resistance Vessels
Daniel R. Hyduke and James C. Liao, Chemical & Biomolecular Engineering, UCLA, 5531 Boelter Hall, 420 Westwood Pl, Los Angeles, CA 90095 |
A Novel, Quantifiable Three-Dimensional Model of Melanoma Invasion
Cyrus M. Ghajar1, Katherine S. Blevins1, Vinod A. Suresh1, Christopher B. Raub1, Steven C. George1 and Andrew J. Putnam2, (1)Biomedical Engineering, University of California, Irvine, Natural Sciences II, Room 3120, Irvine, CA 92697-2715, (2)Biomedical Engineering and Chemical Engineering and Materials Science, University of California, Irvine, Natural Sciences II, Room 3120, Irvine, CA 92697-2715 |
Parsing the Crosstalk between Prominent Oncogenic Signaling Pathways
Nicholas A. Graham, California Institute of Technology, 1200 E. California Blvd, MC 210-41, Pasadena, CA 91125 and Anand R. Asthagiri, Chemistry and Chemical Engineering, California Institute of Technology, 1200 E. California Blvd, MC 210-41, Pasadena, CA 91125 |
Mitochondria Depolarizing Peptides Sensitize Prostate Cancer Cells to Death Receptor Mediated Apoptosis
Kaushal Rege and Martin L. Yarmush, The Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, 51 Blossom St, Boston, MA 02114 |
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Fibrin-Cd44v Binding Interferes with Platelet-Colon Carcinoma Cell Adhesion under High Shear Conditions
Christina S. Alves, Susan L. Napier, Parag Pawar and Konstantinos Konstantopoulos, Chemical and Biomolecular Engineering, Johns Hopkins University, 3400 North Charles St., Baltimore, MD 21218 |
Ultrasound-Enhanced Chemotherapy and Gene Delivery for Gliosarcoma Cells
Vladimir G. Zarnitsyn, George W. Woodruff School of Mechanical Enginnering, Georgia Institute of Technology, 801 Ferst Drive, Atlanta, GA 30332-0405, Pavel Kamaev, School of Medicine, University of Virginia, Charlottesville, VA 22903 and Mark R. Prausnitz, School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, 801 Ferst Drive, Atlanta, GA 30332-0405 |
Tnf-a Based Accentuation of Cryoinjury for the Treatment of Prostate Cancer-Dose, Delivery and Response
Raghav Goel, Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, David Swanlund, University of Minnesota, Minneapolis, MN 55455, James Coad, Department of Pathology, West Virginia University, Morgantown, WV 26506, Guilio Paciotti, Cytimmune Sciences, Inc, Rockville, MD 20850 and John Bischof, Departments of Biomedical and Mechanical Engineering, University of Minnesota, Minneapolis, MN 55455 |
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