Preliminary Program subject to change
TA004 Multiscale Systems Biology
OverviewA fundamental goal of systems biology is to integrate different component parts of a biological system to understand the workings of the whole. Oftentimes the whole biological system will span either multiple time or spatial scales, if not both. The goal of this session is to discuss research that allows us to better understand such multiscale systems. Papers on both experimental and computational studies are welcome.
Primary SponsorTopical A: Systems Biology (TA)

Chair

Christina Chan
Associate Professor
Chemical Engineering and Material Science
Michigan State University
2527 Engineering Building
East Lansing, MI 48824
Phone Number: (517) 432-4530
Fax Number: (517) 432-1105
Email: krischan@egr.msu.edu

CoChair

Stas Shvartsman
Assistant Professor
Department of Chemical Engineering and Lewis-Sigler Institute for Integrative Genomics
Princeton University
Princeton, NJ 08544
Phone Number: 609-258-4694
Fax Number: 609-258-0211
Email: stas@princeton.edu
A Multiscale Model for Cytoskeletal Mechanics
Mohammad R. K. Mofrad, Department of Bioengineering, University of California, Berkeley, 483 Evans Hall #1762, Berkeley, CA 94720
Multiscale Simulation of Breast Cancer Tumorigensis Using Single Cell Models and Kinetic Monte Carlo
Volkan Akcelik1, Lie-Quan Lee1, Satyaprakash Nayak2, Kwok Ko1 and Jeffrey D. Varner2, (1)Advanced Computation Department (ACD), Stanford Linear Accelerator Center (SLAC), Stanford University, Palo Alto, CA 94304, (2)Chemical and Biomolecular Engineering, Cornell University, Olin Hall, Ithaca, NY 14853
Integration of Signal Transduction in Wound Invasion
Michael Monine, Chemical & Biomolecular Engineering, North Carolina State University, Raleigh, NC 27695-7905 and Jason Haugh, Chemical & Biomolecular Engineering, North Carolina State University, Raleigh, NC 27695
Infectious Disease Engineering, Analysis and Simulation of Leishmania Major, a Pathogenic Trypanosomatid
Arvind K. Chavali, Jeffrey D. Whittemore and Jason A. Papin, Department of Biomedical Engineering, University of Virginia, Box 800759, Health System, Charlottesville, VA 22908
Integrated Modeling of Angiotensin II Induced Neuronal Plasticity in the Brain
Rajanikanth Vadigepalli, Dirk Fey and James S. Schwaber, Daniel Baugh Institute for Functional Genomics and Computational Biology, Thomas Jefferson University, 1020 Locust St Room 575, Philadelphia, PA 19107
Signal Dynamics in Sonic Hedgehog Tissue Patterning
Krishanu Saha, Univ. of California-Berkeley, 201 Gilman Hall, Berkeley, CA 94720 and David V. Schaffer, Chemical Engineering, University of California, Berkeley, 201 Gilman Hall, Berkeley, CA 94707
Exploring Biosynthetic Control in Lipid Metabolism
Michael C. Jewett1, Intawat Nookaew2, Francisco A. Pizarro3, Lars I. Hellgren4, Eduardo Agosin3 and Jens Nielsen1, (1)Center for Microbial Biotechnology, Technical University of Denmark, BioCentrum-DTU, Kgs. Lyngby, 2800, Denmark, (2)Department of Chemical Engineering, King Mongkut’s University of Technology Thonburi, Bangkok, 10140, Thailand, (3)Department of Chemical and Bioprocess Engineering, Pontificia Universidad Católica de Chile, Av. Vicuña Mackenna 4860, Santiago, Chile, (4)BioCentrum-DTU, Biochemistry and Nutrition Group, Technical University of Denmark, Building 224, Kgs. Lyngby, 2800, Denmark
Systematically Bridging Transcriptional Regulation and Metabolic Phenotype
Joel Moxley, Chemical Engineering, MIT, 77 Massachusetts Ave, Cambridge, MA 02139, Michael C. Jewett, Center for Microbial Biotechnology, Technical University of Denmark, BioCentrum-DTU, Kgs. Lyngby, 2800, Denmark and Gregory N. Stephanopoulos, Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave., 56-439, Cambridge, MA 02139

Topical A: Systems Biology