Preliminary Program subject to change
TA005 Synthetic Systems Biology I
OverviewSystems biology is the study of whole biological ensembles, rather than isolated parts, in order to build a predictive biological understanding of a defined system’s behavior. Synthetic biology has been defined as the design and construction of systems that exhibit complex dynamical or logical behavior. The intersection between these two fields is likely to significantly enhance efforts in design-based biological engineering and therefore greatly increase human capability. This session will cover current applications of systems biology theory and techniques to aid in the design of synthetic biological systems. In addition, efforts that apply synthetic biology research as new tools to expand systems-level understanding or as new concepts in systems biology are of interest.
Primary SponsorTopical A: Systems Biology (TA)

Chair

Christina Smolke
Assistant Professor
Division of Chemistry & Chemical Engineering
CalTech
Pasadena, CA 91125
Phone Number: 626-395-2460
Email: smolke@cheme.caltech.edu

CoChair

Jason Haugh
Associate Professor
Chemical & Biomolecular Engineering
North Carolina State University
Box 7905, Engineering Bldg. I
911 Partners Way
Raleigh, NC 27695-7905
Phone Number: (919) 513-3851
Fax Number: (919) 515-3465
Email: jason_haugh@ncsu.edu
Genetic Circuits to Build Biopolymers
Christopher Voigt, Pharmaceutical Chemistry, University of California - San Francisco, Box 2540, 1700 4th Street, San Francisco, CA 94143
Substrate Specificity and Domain Interaction of the 6-Deoxyerythronolide B Synthase
Alice Yu-Chieh Chen, Chemical Engineering, Stanford University, 1301B Lyman Residence, 121 Campus Drive, Stanford, CA 94305 and Chaitan Khosla, Chemical Engineering, Stanford University, Keck 389, 380 Roth Way, Stanford, CA 94305
Re-Engineering in Vivo Signal Processing
Stephen A. Chapman, California Institute of Technology, 1200 E. California Blvd MC 210-41, Pasadena, CA 91125 and Anand R. Asthagiri, Chemical Engineering, California Institute of Technology, 1200 E. California Blvd MC 210-41, Pasadena, CA 91125
Biosynthesis of Cadmium Sulfide Semiconductor Nanocrystals
Seung Hyun Kang, Ashok Mulchandani and Wilfred Chen, Department of Chemical and Environmental Engineering, University of California, Riverside, Riverside, CA 92521
A Detailed Kinetic Model for a Bistable Genetic Network
Aditya Pratap Singh, Department of Chemical Engineering, University of Delaware, Allan P. Colburn Lab, 150 Academy Street, Newark, DE 19716 and Jeremy S. Edwards, Chemical and Nuclear Engineering, University of New Mexico
Enhancement of Cellular Memory by Reducing Stochastic Transitions
Murat Acar, Attila Becskei and Alexander van Oudenaarden, Physics, Massachusetts Institute of Technology, Cambridge, MA 02139-4307
Stochastic Simulation Analysis of Metabolic Channeling for the Production of R-1,2 Propanediol
Robert J. Conrado, Thomas J. Mansell, Jeffrey D. Varner and Matthew P. DeLisa, Department of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14850

Topical A: Systems Biology