Preliminary Program subject to change
TA007 In Silico Systems Biology II
OverviewA critical component of systems biology is the development of in silico approaches to understand systems of interest. For this session, papers discussing novel uses of in silico methods to understand biological systems, as well as the development of new technologies and algorithms for in silico systems analysis are welcome. Research including experimental work is particularly encouraged.
Primary SponsorTopical A: Systems Biology (TA)

Chair

Jeffrey D. Varner
Assistant Professor
Chemical and Biomolecular Engineering
Cornell University
Olin Hall
Ithaca, NY 14853
Phone Number: (607) 255 8656
Fax Number: (607) 255 9166
Email: jdv27@cornell.edu

CoChair

Ranjan Srivastava
Assistant Professor
University of Connecticut
191 Auditorium Rd., Unit 3222
Storrs, CT 06269
Phone Number: (860) 486-2802
Fax Number: (860) 486-2959
Email: srivasta@engr.uconn.edu
In Silico Bacterial Cells: from Generalized Coarse-Grained to Genome-Specific Modular Models
Jordan C. Atlas1, Evgeni V. Nikolaev2 and Michael L. Shuler1, (1)School of Chemical and Biomolecular Engineering, Cornell University, 120 Olin Hall, Ithaca, NY 14853, (2)Biomedical Engineering, Cornell University, 270 Olin Hall, Ithaca, NY 14853
Bifurcation Analysis of Stochastic Gene Networks
Howard Salis, Department of Chemical Engineering and Materials Science, University of Minnesota, 151 Amundson Hall, 421 Washington Ave SE, Minneapolis, MN 55455 and Yiannis N. Kaznessis, Chemical Engineering. and Materials. Science, University of Minnesota, 499, Walter Library, 117, Pleasant St. SE, Minneapolis, MN 55455
Novel Framework for Identifying Objective Functions of Biological Systems
Erwin P. Gianchandani, Matthew A. Oberhardt, Jong Min Lee and Jason A. Papin, Department of Biomedical Engineering, University of Virginia, Box 800759, Health System, Charlottesville, VA 22908
Modelling Amino Acid Metabolism in Mammalian Cells - Towards the Development of a Model Library
Cleo Kontoravdi1, Carolyn M. C. Lam1, Yih Yean Lee2, Danny C. F. Wong2, Miranda G. S. Yap2, Efstratios N. Pistikopoulos1 and Athanasios Mantalaris1, (1)Department of Chemical Engineering, Imperial College London, South Kensington campus, London, SW7 2AZ, United Kingdom, (2)Agency for Science and Technology Research (A*STAR), 20 Biopolis Way, #06-01, Centros, Singapore, 138668, Singapore
Break
Cell-Cell Crosstalk Potentiates Cell Patterning during Development
Claudiu A. Giurumescu1, Paul W. Sternberg2 and Anand R. Asthagiri1, (1)Chemistry and Chemical Engineering, California Institute of Technology, 1200 E. California Blvd, MC 210-41, Pasadena, CA 91125, (2)Division of Biology, California Institute of Technology, 1200 E. California Blvd., Pasadena, CA 91125
Regulation of the Sh2 Domain-Containing Protein-Tyrosine Phosphatase Shp2 in Receptor Signaling: Kinetic Model and Structure-Based Analysis
Dipak Barua1, James Faeder2 and Jason Haugh1, (1)Chemical & Biomolecular Engineering, North Carolina State University, Raleigh, NC 27695, (2)Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, NM 87545
Molecular Signatures That Differentiate Cancer Subtype and Predict Clinical Outcome
Nathan D. Price1, Ilya Shmulevich1, Biaoyang Lin1, Wei Zhang2, Nicole Urban3, Charles Drescher3 and Leroy Hood1, (1)Institute for Systems Biology, 1441 N. 34th Street, Seattle, WA 98103, (2)Pathology and Cancer Biology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, (3)Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N., Seattle, WA 98109

Topical A: Systems Biology