Preliminary Program subject to change
08B09 Approaches for Non-Viral Gene Delivery
OverviewThis session will cover the design, synthesis and evaluation of materials for non-viral delivery of genetic material in vitro and in vivo.
Primary SponsorBiomaterials (08b)

Chair

David M. Lynn
Assistant Professor
University of Wisconsin - Madison
1415 Engineering Drive
Madison, WI 53706
Phone Number: 608-262-1086
Fax Number: 608-262-5434
Email: dlynn@engr.wisc.edu

CoChair

Christina Chan
Associate Professor
Chemical Engineering and Material Science
Michigan State University
2527 Engineering Building
East Lansing, MI 48824
Phone Number: (517) 432-4530
Fax Number: (517) 432-1105
Email: krischan@egr.msu.edu
Engineering Cellular Niches to Regulate Non-Viral Gene Delivery
Hyun Joon Kong1, Susan Hsiong2 and David J. Mooney1, (1)Division of Engineering and Applied Science, Harvard University, 40 Oxford Street 415, Cambridge, MA 02138, (2)Chemical Engineering, University of Michigan, Ann Arbor, MI 48109
Incorporation of Polyethylene Glycol into Self-Assembled Monolayers Enhances Substrate-Mediated Gene Delivery by Nonspecifically- Bound Complexes
Angela K. Pannier and Lonnie D. Shea, Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Rd/ TECH E136, Evanston, IL 60208
Engineering Aptamer and SIRNA Based Drug Delivery Systems Using Polyelectrolyte Multilayer Films
Srivatsan Kidambi, Department of Chemical Engineering and Materials Science, Michigan State University, 2527, Engineering Building, East Lansing, MI 48824, Ilsoon Lee, Michigan State University, Department of Chemical Engineering and Materials Science, 2527 Engineering Building, East Lansing, MI 48824 and Christina Chan, Chemical Engineering and Material Science, Michigan State University, 2527 Engineering Building, East Lansing, MI 48824
Ternary Particles for Sustained Gene Delivery
Treniece L. Terry, Department of Chemical and Biochemical Engineering, University of Iowa, 4133 Seamans Center, Iowa City, IA 52242, Victor G. J. Rodgers, Bioengineering, The University of California, Riverside, The Marlan and Rosemary Bourns College of Engineering, Bourns Hall, Room A242, Riverside, CA 92521 and Aliasger K. Salem, Division of Pharmaceutics, College of Pharmacy and Department of Chemical and Biochemical Engineering, College of Engineering, University of Iowa, 115 S. Grand Avenue, S228 PHAR, Iowa City, IA 52242
Design and Characterization of Targeted Nanoparticles for Systemic Gene Delivery
Derek W. Bartlett and Mark E. Davis, Chemical Engineering, California Institute of Technology, 1200 E. California Blvd., MC 210-41, Pasadena, CA 91125
Micelleplexes: Terpolymer Micelle-Based Gene Delivery Vectors with Superior DNA Protection against Enzymatic Degradation
Rahul Sharma, Jae-Sung Lee and You-Yeon Won, School of Chemical Engineering, Purdue University, 480 Stadium Mall Drive, West Lafayette, IN 47907
A Modified Polyethylenimine for Light-Triggered DNA Release
Rachel G. Handwerger, Bioengineering, University of Pennsylvania, 1150 Vagelos Labs, 3340 Smith Walk, Philadelphia, PA 19104, Moon-Suk Kim, Medicinal Science, Korea Research Institute of Chemical Technology, Yuseong, Daejeon, 305-600, South Korea and Scott L. Diamond, Chemical and Biomolecular Engineering, University of Pennsylvania, 1024 Vagelos Research Labs, 3340 Smith Walk, Philadelphia, PA 19104
Ferrocene-Containing Cationic Lipids for Gene Delivery: Oxidation State Determines Transfection Activity
Christopher M. Jewell1, Melissa E. Hays1, Yukishige Kondo2, Nicholas L. Abbott1 and David M. Lynn1, (1)University of Wisconsin - Madison, 1415 Engineering Drive, Madison, WI 53706, (2)Department of Industrial Chemistry, Tokyo University of Science, Tokyo, Japan

Materials Engineering and Sciences Division