| This session will focus on Metabolic Engineering as a molecular-systems approach to the understanding and utilization of metabolic processes. The goal of the session is to discuss very recent advances in modeling and experimental approaches necessary to understand the integration and control of genetic, catalytic, and other biochemical events that govern cellular metabolism. Topics of interest include: reconstruction of metabolic as well as gene regulatory networks; control analysis; genomic, proteomic and/or metabolomic analysis; optimization; and heterologous pathways. We invite papers on the development and application of these techniques to cells derived from plant, insect, and animal tissues. |
Understanding Cofactor Partitioning in Xylitol-Producing Escherichia Coli Expressing Xylose Reductase
Jonathan W. Chin, Chemical Engineering, Penn State University, 222 Fenske Lab, University Park, PA 16802, Costas D. Maranas, Department of Chemical Engineering, The Pennsylvania State University, University Park, PA 16802 and Patrick C. Cirino, The Pennsylvania State University, 226 Fenske Lab, University Park, PA 16802 |
Metabolic Control Analysis Provides Insights into Strategies for Improving Ethanol Production from Recombinant Xylose-Utilizing Saccharomyces Cerevisiae
Liqing Wang, Department of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Road, Room E136, Evanston, IL 60208-3120 and Vassily Hatzimanikatis, Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Rd., Evanston, IL 60208 |
Simultaneous Estimation of Reaction Fluxes and Metabolite Levels Using Instationary 13C Metabolic Flux Analysis
Jamey D. Young, Jason L. Walther, Maciek R. Antoniewicz and Gregory N. Stephanopoulos, Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave., 56-439, Cambridge, MA 02139 |
Total Microbial Synthesis of Benzylisoquinoline Alkaloids in Saccharomyces Cerevisiae
Kristy M. Hawkins and Christina Smolke, Chemical Engineering, California Institute of Technology, Pasadena, CA 91125 |
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Forward Engineering of a S. Coelicolor Actinorhodin Overproducer Using Transposon Mutagenesis
Elizabeth Widenbrant and Camilla M. Kao, Chemical Engineering, Stanford University, 381 N-S Drive, Stauffer 3, Rm 113, Stanford, CA 94305 |
Engineering of Organic Acid Tolerance Genes in E. Coli for Biorefinery Applications
Tanya Warnecke1, Michael D. Lynch2, Nicholas R. Sandoval1 and Ryan T. Gill1, (1)Department of Chemical and Biological Engineering, University of Colorado, ECCH 111 Campus Box 424, Boulder, CO 80309, (2)University of Colorado, ECCH 111, Campus Box 424, Boulder, CO 80309 |
Biosynthesis of Fosfomycin
Zengyi Shao, University of Illinois, Urbana-Champaign, 600 S. Mathews, RAL 221, Box C-3, Urbana, IL 61801, Ryan Woodyer, Chemistry, University of Illinois, Urbana-Champaign, 600 S. Mathews, RAL 221, Box C-3, Urbana, IL 61801 and Huimin Zhao, Chemical&Biomolecular Engineering, University of Illinois, Urbana-Champaign, 600 S. Mathews, RAL 221, Box C-3, Urbana, IL 61801 |
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