Preliminary Program subject to change
15D11 Gene Therapy and Delivery (II)
OverviewThis session will be devoted to the development of improved methods of gene transfer using both viral and non-viral approaches. Topics of interest include, but not limited to design of novel formulations for improved gene delivery, determination of rate-limiting steps of gene transfer, targeting of gene transfer vectors, methods for production and purification of viral and non-viral vectors and gene transfer to stem cells for tissue engineering applications. This session has been very well attended in previous years.
Primary SponsorEngineering Fundamentals in Life Science (15d)

Chair

Stelios T. Andreadis
Professor
Chemical and Biological Engineering
SUNY-Buffalo
303 Furnas Hall
Buffalo, NY 14260
Phone Number: 716-645-2911
Email: sandread@eng.buffalo.edu

CoChair

Joseph M. Le Doux
Associate Professor
Biomedical Engineering
Georgia Institute of Technology
Atlanta, GA 30332
Phone Number: 404-385-0632
Email: joe.ledoux@bme.gatech.edu
Immunization Via Skin Using Vaccine-Coated Microneedles
Harvinder S. Gill1, Jonas Soderholm2, Ioanna Skountzou3, Joshy Jacob4, Richard Compans3, Matti Sallberg2 and Mark R. Prausnitz5, (1)The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, 315 Ferst Drive, Atlanta, GA 30332, (2)Division of Clinical Virology, Karolinska Institute, Karolinska University Hospital Huddinge, S-141 86, Stockholm, Sweden, (3)Department of Microbiology and Immunology, Emory University, 1510 Clifton Road, Rollins Research Center, Rm 3108, Atlanta, GA 30322, (4)The Emory Vaccine Center, Emory University, 954 Gatewood Rd, Atlanta, GA 30329, (5)Chemical and Biomolecular Engineering, Biomedical Engineering, Georgia Institute of Technology, 311 Ferst Drive, Atlanta, GA 30332-0100
Construction of Hybrid Viral/Synthetic Gene Delivery Nanovectors
Josh Ramsey, Halong Vu and Daniel W. Pack, Chemical and Biomolecular Engineering, University of Illinois, Box C-3, 600 S. Mathews Ave., Urbana, IL 61801
Using RNA Interference to Probe Mechanism: Dnase II Is Not Rate Limiting in Non-Viral Gene Transfer to Endothelium
Gregory A. Barker and Scott L. Diamond, Chemical and Biomolecular Engineering, University of Pennsylvania, 1150 Vagelos Labs, 3340 Smith Walk, Philadelphia, PA 19104
Egf Ligands Decrease Retroviral Gene Transfer through Protein Kinase C-Delta
Raghvendra Singh, SUNY at Buffalo, 303 Furnas Hall, Dept. of Chemical Engg, University at Buffalo (North Campus), Amherst, NY 14260 and Stelios T. Andreadis, SUNY at Buffalo, 908 Furnas Hall, Amherst, NY 14260
Break
Expression-Targeted Gene Therapy for the Treatment of Transitional Cell Carcinoma
Xiujuan Zhang1, Anthony J. Atala2 and W. T. Godbey1, (1)Chemical & Biomolecular Engineering, Tulane University, 300 Lindy Boggs Center, 6823 St. Charles Ave, New Orleans, LA 70118, (2)Wake Forest University Baptist Medical Center, Winston-Salem, NC
Analysis of Retroviral Decay: Protein and RNA Stability
Monica Casali1, Jonathan Goldwasser2, Z. Larkin Kelley1, Zaki Megeed1 and Martin L. Yarmush1, (1)Center for Engineering in Medicine, 51 Blossom Street, Boston, MA 02114, (2)Harvard-MIT Division of Health Sciences and Technology, Center for Engineering in Medicine, 51 Blossom Street, Boston, MA 02114
Engineering Outer Membrane Vesicles for Gene Delivery
David Chen1, Jae-Young Kim1, Anne Doody2, Matthew Delisa1 and David Putnam2, (1)School of Chemical and Biomolecular Engineering, Cornell University, 120 Olin Hall, Ithaca, NY 14853, (2)Department of Biomedical Engineering, Cornell University, 120 Olin Hall, Ithaca, NY 14853

Food, Pharmaceutical & Bioengineering Division