An Ontology-Based Information Management System for Pharmaceutical Product Development
Leaelaf Hailemariam1, Chunhua Zhao2, Girish Joglekar1, David Whittinghill3, Ankur Jain1, Venkat Venkatasubramanian1, Gintaras V. Reklaitis1, Kenneth R. Morris4 and Prabir K. Basu5, (1)School of Chemical Engineering, Purdue University, Forney Hall of Chemical Engineering, 480 Stadium Mall Drive, West Lafayette, IN 47907-2100, (2)Bayer Technology and Engineering (Shanghai) Co. Ltd, Shanghai, 201507, China, (3)Information Technology at Purdue, Ernest C Young Hall, 302 Wood Street, West Lafayette, 47907, (4)Industrial and Physical Pharmacy, Purdue University, 575 Stadium Mall Drive, West Lafayette, IN 47907-2088, (5)Purdue University, 315 Hovde Hall, 610 Purdue Mall, West Lafayette, IN 47906-2040 |
Optimization of Solvent Chasing Distillation in Pharmaceutical Industry
David Li1, Jenny Lau2, ChenXi Yang2, Stephen Tyler2 and Kelley Ford2, (1)Global Pharmaceutical Operations, Manufacturing Science and Technology, Dept 045B, Building R13-2,, Abbott Laboratories, 1401 Sheridan Road, North Chicago, IL 60064, (2)Abbott Laboratories, 1401 Sheridan Road, North Chicago, IL 60064 |
Protein Stabilization by Chemical Stabilizers: Molecular Dynamic Simulation and Experimental Validation
Diannan Lu, Tsinghua University, Department of Chemical Engineering, Beijing, 100084, China and Zheng Liu, Chemical Engineering, Tsinghua University, Department of Chemical Engineering, Beijing, 100084, China |
Development of a Robust Process for Harvesting Bioreactors
Christina L. Alexander1, Parviz A. Shamlou2, Lawrence H. Breen2 and Sigma S. Mostafa1, (1)Bioprocess Research and Development, Eli Lilly and Company, Indianapolis, IN 46221, (2)Process Engineering Center, Eli Lilly and Company, Indianapolis, IN 46221 |
Trouble-Shooting of Glassy and Ball Material Formulation during Drying of Api Wet Cake
Yubo Yang, MS&T Process Sciences and Engineering, Abbott Laboratories, 1401 Sheridan Road, North Chicago, IL 60064 and Stephen Tyler, Abbott Laboratories, 1401 Sheridan Road, North Chicago, IL 60064 |
Optimization of Monoclonal Antibody Production Using Process Simulation and Scheduling Tools
Charles Siletti, INTELLIGEN, INC., 700 Walton Ave., Mount Laurel, NJ 08054 and Demetri P. Petrides, INTELLIGEN, INC., 2326 Morse Avenue, Scotch Plains, NJ 07076 |
Developing a Systematic Design Approach to Tailor Crystal Size Distribution for Mixing-Sensitive Crystallization Processes
Xing Yi Woo, National University of Singapore & University of Illinois, 4 Engineering Drive 4, Singapore, 117576, Singapore, Reginald B. H. Tan, Department of Chemical and Biomolecular Engineering, The National University of Singapore, 4 Engineering Drive 4, 117576, Singapore and Richard D. Braatz, University of Illinois, 600 South Mathews Avenue, 93 Roger Adams Laboratory, Box C-3, Urbana, IL 61801-3602 |
Inverse-Qsar for Inhibitors of Phosphate Cdc25b
Derick C. Weis, Chemical Engineering, Tennessee Technological University, Cookeville, TN 38505, Donald P. Visco Jr., Chemical Engineering, Tennessee Technological University, Box 5013, Cookeville, TN 38505 and Jean-Loup Faulon, Computational Biology Department, Sandia National Laboratories, Albuquerque, NM 87185 |
Measuring and Simulation of the Concentration Profile of Binary Mixtures of Powders When Flowing between Flat Plates with Rough Surfaces
Luis Guillermo Obregon, Chemical Engineering, University of Puerto Rico at Mayaguez Campus, P.O. Box 5997, Mayaguez, PR 00681 and Carlos Velazquez, Chemical Engineering, University of Puerto Rico at Mayaguez Campus, PO Box 9046, Mayaguez, PR 00681 |
Application of Raman Microscopy and Band-Target Entropy Minimization to Identify Trace Compounds in Model Pharmaceutical Tablets
Effendi Widjaja and Regina Kim Hong Seah, Process Science and Modeling, Institute of Chemical and Engineering Sciences, 1 Pesek Road, Jurong Island, Singapore, 627833, Singapore |
The Effect of a New Pressure Change Technology on Microorganisms, an Innovate Concept for Food and Pharmaceutical Safety
Reiner Staudt, Institut f. Nichtklassische Chemie e.V., Permoserstr. 15, Leipzig, 04275, Germany, Katrin Bönsch, Sächsiches Institut für angewandte Biotechnologie e.V., Permoserstr. 15, Leipzig, 04318, Germany, Jelka Ondruschka, Sächsisches Institut für angewandte Biotechnologie e.V., Permoserstr. 15, Leipzig, 04318, Germany and Mike Wecks, Institut f. Nichtklassische Chemie e.V., Permoserstr. 15, Leipzig, 04318, Germany |
Catalyst Trap Microreactor for Pharmaceutical Hydrogenation Reaction
Shaun M. McGovern1, G. Harish2 and Ronald S. Besser2, (1)Chemical, Biomedical and Materials Engineering, Stevens Institute of Technology, Castle Point on Hudson, Hoboken, NJ 07030, (2)Chemical, Biomedical, and Materials Engineering, Stevens Institute of Technology, Castle Point on Hudson, Hoboken, NJ 07030 |
Linear Mixed-Effects Models in the Mathematica® Environment
Laurent Simon, Otto H. York Department of Chemical Engineering, New Jersey Institute of Technology, University Heights, Newark, NJ 07102 |
Operational Challenges of Large Scale Monoclonal Antibody Bulk Production for Clinical Trial Delivery
James Varughese1, Arun Kejariwal1, T. Craig Seamans2, Celestine Chang1, Dean Caravoulias1 and Jeffrey Strekas1, (1)Bioprocess Clinical Manufacturing and Technology, Merck & Co., Inc., West Point, PA 19486, (2)Biocatalysis and Fermentation, Merck & Co., Inc., Rahway, NJ 07065 |
Phytochemical Composition and Antimicrobial Activity of the Essential Oil from Echinophora Platyloba DC
Somayeh Farsi1, Gholamreza Asghari1, Daryoush Abedi2 and Mohammad Jalali3, (1)Departmet of Pharmacognosy, Faculty of Pharmacy and Pharmaceutical Sciences,, Isfahan University of Medical Sciences, Isfahan, 81746-73461, Iran, (2)Departmet of Pharmaceutical Biotechnology, Faculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, 81746-73461, Iran, (3)Department of Nutrition, Faculty of Health, Isfahan University of Medical Sciences, Isfahan, 81445-04500, Iran |
Mechanical Property Characterization of Active Pharmaceutical Ingredients
Steve S. Y. Wang, Steven H. Chan and San Kiang, Bristol-Myers Squibb Company, One Squibb Drive, New Brunswick, NJ 08903 |
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