Carbon catabolite repression (CCR) in bacteria takes up one carbon source preferentially from a mixture in the growth medium and utilizes carbohydrate uptake according to the metabolic capacities of the cell.

Although fundamental biochemical principles of the carbon catabolite repression network have been understood, a quantitative description of this growth behavior is still lacking. We study the network regulating the cell-cycle of carbon catabolite repression in bacteria using a simple dynamical model to investigate its global property and stability. It is shown that the cell-cycle regulatory network is extremely stable and robust for its function. We also analyze the preferential utilization for different sugar sources.

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