Preliminary Program subject to change
TI000 Absorption of Oral Dosage Forms
OverviewPapers are invited from industry and academia on cutting edge studies focusing on the absorption and bioavailability of oral dosage forms. Subjects include and are not limited to: formulation design and bioavailability enhancing platforms, modeling of the pharmacokinetic, absorption, and hydrodynamic profiles of dosage forms within the GI tract, in-vitro-in-vivo correlations for dissolution of oral dosage forms, innovative processing techniques in controlled release and immediate release oral delivery, and studies relating GI physiology to absorption profiles.
Primary SponsorTopical I: Pharmaceutical Engineering for the 21^st Century (TI)
Co-Sponsor(s)Pharmaceuticals (15b)

Chair

Padma J. Narayan
Principal Scientist
Transform Pharmaceuticals Inc.
29 Hartwell Ave
Lexington, MA 02421
Phone Number: 781-674-7819
Fax Number: 781-863-7247
Email: pnaraya3@TPIUS.JNJ.COM

CoChair

Monica Adams
Scientist
Bristol-Myers Squibb
1 Squibb Drive
New Brunswick,, NJ 08903
Phone Number: 732-227-6125
Email: monica.adams@bms.com
Oral Absorption of Weakly Acidic Compounds
Monica L. Adams, Venkatramana Rao, James Ormes and Ajit Thakur, Biopharmaceutics Research and Development, Bristol-Myers Squibb, One Squibb Drive, New Brunswick, NJ 08903
Oral Delivery of Insulin-Transferrin Bioconjugates Using Intelligent Complexation Hydrogels
Justin P. Shofner and Nicholas A. Peppas, Department of Chemical Engineering, University of Texas at Austin, 1 University Station C0400, Austin, TX 78712
Development of A Computer Program Predicting the Influence of Cyclodextrins on Oral Bioavailability of Insoluble Drugs: From Modeling to in Vivo Comparison
Ece D. Gamsiz, Deparment of Chemical Engineering, Northeastern University, 342 Snell Engineering Center, Boston, MA 02115, Lee A. Miller, Pfizer Global Research and Development, Ann Arbor, MI, Avinash G. Thombre, Pfizer, Inc., Eastern Point Road, Groton, CT 06340 and Rebecca L. Carrier, Department of Chemical Engineering, Northeastern University, 342 Snell Engineering Center, Boston, MA 02115
Using Physically-Based Dissolution Simulations to Develop Ideal Particle Distributions in Tablets
Dan Braido, Rutgers University, 98 Brett rd., Piscataway, NJ 08854 and Alberto Cuitino, Mechanical Engineering, Rutgers University, 98 Brett rd., Piscataway, NJ 08854
A New Hypromellose Excipient for Direct Compression Controlled Release
Karl Jacob1, Kacee Ender2, Tim Cabelka2, Dan Denomme2 and Dave Wallick2, (1)The Dow Chemical Company, 1319 Bldg, Midland, MI 48667, (2)Water Soluble Polymers R&D, The Dow Chemical Company, Larkin Lab, Midland, MI 48674
Sublingual Drug Delivery; Will It Always Give ‘Fast Onset'? A Product Enhancement Perspective
Jeremy A. Bartlett, Oral Products Center of Emphasis, Pfizer Inc., Eastern Point Road MS#8156-042, Groton, CT 06340

Topical I: Pharmaceutical Engineering for the 21Century