Preliminary Program subject to change
15B04 Protein Drug Formulation and Delivery
OverviewThe focus of this session is on the development and implementation of formulations and delivery systems for protein therapeutics. Specific topics of interest include scale up of formulation processes, and the impact of drug product delivery systems.
Primary SponsorPharmaceuticals (15b)
Co-Sponsor(s)Engineering Fundamentals in Life Science (15d)

Chair

Monica Pallitto
Amgen
1201 Amgen Ct W
Seattle, WA 98119
Phone Number: 206-265-7856
Email: monicap@amgen.com

CoChair

Rebecca L. Carrier
Department of Chemical Engineering
Northeastern University
342 Snell Engineering Center
360 Huntington Avenue
Boston, MA 02115
Phone Number: 617-373-7126
Email: rebecca@coe.neu.edu
Temperature-Induced Release from Double Emulsions as a Potential Transcutaneous-Immunization Method
Edith C. Rojas1, Vijay T. John2 and Kyriakos D. Papadopoulos2, (1)Chemical and Biomolecular Engineering Department, Tulane University, 300 Lindy Boggs Bldg., New Orleans, LA 70118, (2)Chemical and Biomolecular Engineering, Tulane University, 300 Lindy Boggs Bldg., New Orleans, LA 70118
Molecular Design And Dynamic Behavior Of Interpolymer Complexing Hydrogels As Carriers For The Oral Delivery Of Therapeutic Proteins
Daniel A. Carr1, Wesley A. Hunt2 and Nicholas A. Peppas1, (1)Department of Chemical Engineering, The University of Texas at Austin, 1 University Station C0400, Austin, TX 78712, (2)Department of Biomedical Engineering, The University of Texas at Austin, 1 University Station C0400, Austin, TX 78712
Evaluation Of Protein Release Rate From Thermosensitive Hydrogel Using Poly (N-Isopropylacrylamide)-Co-Poly (2-Hydroxyethyl Methacrylate)
Masaki Kubo, Takafumi Matsuyama and Toshikuni Yonemoto, Department of Chemical Engineering, Tohoku University, Aoba-yama 6-6-07, Sendai, 980-8579, Japan
Controlled Release of Insulin by Duo-Functional Injectable Hydrogel
Dai Phu Huynh, Bong Sup Kim and Doo Sung Lee, Polymer Science & Engineering, SungKyunKwan University, Jangan-ku, Kyungki 440-746, Suwon, South Korea
Break
Stable Protein Nanoparticles Produced By Rapid Freezing For Enhanced Delivery
Keith P. Johnston1, Joshua D. Engstrom2, Jamine Tam2, Edwina Lai2 and Robert Williams2, (1)Department of Chemical Engineering, The University of Texas at Austin, 1 University Station C0400, Austin, TX 78712, (2)The University of Texas at Austin, 1 University Station C0400, Austin, TX 78712
Novel Propellant-Driven Formulations For The Pulmonary Delivery Of Biomolecules: Particle Engineering, Aerosol Characteristics And In Vitro Toxicity
Balaji S. Bharatwaj1, Libo Wu1 and Sandro R. P. Da Rocha2, (1)Chemical Engineering and Materials Science, Wayne State University, Room No. 1133 Eng, 5050 Anthony Wayne Drive, Detroit, MI 48202, (2)Chemical Engineering and Materials Science, Wayne State University, 5050 Anthony Wayne Drive, Detroit, MI 48202
Understanding Protein Transcytosis To Engineer Efficient Therapeutics
Pankaj Karande, Chemical Engineering, Massachusetts Institute of Technology, E19-563, Cambridge, MA 02139 and K. Dane Wittrup, Chemical Engineering and Biological Engineering, Massachusetts Institute of Technology, E19-551, Cambridge, MA 02139

Food, Pharmaceutical & Bioengineering Division