| Preliminary Program subject to change |
| TI007 Modeling in the Pharmaceutical Industry |
| We invite contributions from industry and academia that address system-level process simulation (cycle time analysis, mass and energy balances, equipment usage, scheduling etc.) and/or more detailed unit operations modeling during process development and scale-up in pharmaceutical synthesis and formulation (e.g. reaction steps, solvent chasing, crystallization, filtration, drying). Particular consideration will be given to examples of model development from laboratory data with model validation during scale-up and clear savings or greater process understanding as a result of modeling. |
| Topical I: Pharmaceutical Engineering for the 21^st Century (TI) |
| Pharmaceuticals (15b) |
Chair
Victor Hung
Bristol Myers Squibb
New Brunswick, NJ 08902
Phone Number: 410-455-3405
Email: victor.hung@bms.com
CoChair
Joe Hannon
PFD (Dynochem)
Dublin 2, NY
Ireland
Phone Number: 914-945-2597
Email: joe.hannon@scale-up.com
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Opportunities, Challenges, And Approaches For Modeling In The Pharmaceutical Industry
Prashant B. Kokitkar, Engineering Technology Center, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285 |
Modeling of Breakage and Dissolution of Crystals with Varying Particle Size Distribution within the Quality by Design Framework
Pavol Rajniak, Kim Gallagher, Rey Chern, Craig Ikeda and Justin Moser, Merck & Co, Inc., WP78-110, PO Box 4, West Point, PA 19486 |
Application of Modeling in a Qbd Context
James Wertman, GSK, Upper Merion, PA 19406 |
Coater-Dryer Models
Alexander J. Marchut, Wei Chen, Steven H. Chan, Shih-Ying Chang, Olav Lyngberg, Donald Kientzler and San Kiang, Bristol Myers Squibb, New Brunswick, NJ 08903 |
| Break |
Potential of S88, Batchml and Other Standards in Streamlining Process Modeling
Alistair Gillanders, DynoChem Inc., Wilmington, DE 19803 |
Batch Plus Modeling As A Tool To Drive R&d-Based Process Expansion
Samrat Mukherjee, Shekhar Viswanath and Jeffrey Breting, Process R&D, Abbott Laboratories, Dept R452, Bldg R8-3, 1401 Sheridan Rd., North Chicago, IL 60064 |
Application of Agent Technique in Bioprocess Modelling for Plant-Wide Process Improvement
Ying Gao1, Katie Kipling2, Jarka Glassey2, Yuhong Zhou1, Mark Willis2, Gary Montague2 and Nigel Titchener-Hooker1, (1)Biochemical Engineering Department, University College London, Torrington Place, London, WC1E 7JE, United Kingdom, (2)School of Chemical Engineering and Advanced Materials, Newcastle University, Newcastle upon tyne, NE1 7RU, United Kingdom |
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