Delivery And Mechanistic Considerations For The Production Of Knock-In Mice By Single-Stranded Oligonucleotide Gene Targeting
Brian R. Murphy, University of Pennsylvania, 1024 Vagelos Research Laboratories, Philadelphia, PA 19104, Eric A. Pierce, Unniversity of Pennsylvania, 422 Curie Blvd, Philadelphia, PA 19104 and Scott L. Diamond, Department of Chemical and Biomolecular Engineering, University of Pennsylvania, 3340 Smith Walk, 1150 Vagelos Labs, Philadelphia, PA 19104 |
Tuning Antisense Oligonucleotide Backbone Chemistry For Improved Polymer-Mediated Delivery And Gene Silencing
Sumati Sundaram1, Mark Hwang2, Li Kim Lee1 and Charles Roth1, (1)Chemical and Biochemical Engineering, Rutgers University, 98 Brett Road, Piscataway, NJ 08854, (2)Biomedical Engineering, Rutgers University, 599 Taylor Road, Piscataway, NJ 08854 |
Inorganic-Organic Composite Particle as a Staged Delivery Platform for Plasmid DNA-Based Biopharmaceuticals
Jenny Ho1, Gareth M. Forde1 and Huanting Wang2, (1)Bio-Engineering Laboratory (BEL), Department of Chemical Engineering, Monash University, P.O.Box 36, Clayton, 3800, Victoria, Melbourne, Australia, (2)Department of Chemical Engineering, Monash University, P.O.Box 36, Clayton, 3800, Victoria, Melbourne, Australia |
Efficient Nonviral Gene Delivery Using Highly Versatile Degradable Nanoparticle Carriers
Shiwei Lu1, In Kap Ko1, Assem Ziady2 and Young Jik Kwon1, (1)Biomedical Engineering, Case Western Reserve University, 10900 Euclid Ave, Cleveland, OH 44106, (2)Department of Physiology and Biophysics, Case Western Reserve University, 10900 Euclid Ave, Cleveland, OH 44106 |
Multi-Functional Nanoparticals of Micrornas for Tumor-Targeted Gene Therapy
Bo Yu, The Ohio State University, 140 West 19th Avenue, columbus, OH 43210, Yan Jin, NSF Center for Affordable Nanoengineering of Polymeric Biomedical Devices, The Ohio State University, 140 West 19th Avenue, Columbus, OH 43210, Xulang Zhang, The Ohio State University, 140 West 19th Avenue, Columbus, OH 43210, Xiaojuan Yang, Pharmacy department, pharmacy college, 500w.12th Ave, Parks hall, Columbus, OH 43210, Chee Guan Koh, Department of Chemical and Biomolecular Engineering, The Ohio State University, 140 West 19th Avenue, Columbus, OH 43210, Robert J. Lee, College of Pharmacy, The Ohio State University, 542 Parks Hall, 500 West 12th Avenue, Columbus, OH 43210, Natarajan Muthusamy, HEALTH SCIENCES, Comprehensive Cancer Center, 410 W 12TH AVE, COLUMBUS, OH 43210, John Byrd, Hematology & Oncology, CLLEGE OF MEDICINE, B302 STAR LOVNG,320 W 10TH AVE ,OLUMBUS, OH 43210, Columbus and James Lee, Chemical and Biomolecular Engineering, The Ohio State University, Room 125A, Koffolt Labs., 140W. 19th Ave., Columbus, OH 43210 |
Novel Polymer Micelle-DNA Complexes For Targeted in Vivo Gene Delivery
Rahul Sharma1, Stephen F. Konieczny2 and You-Yeon Won1, (1)School of Chemical Engineering, Purdue University, 480 Stadium Mall Drive, West Lafayette, IN 47907, (2)Department of Biological Sciences, Purdue University, 915 W. State Street, West Lafayette, IN 47907 |
Gene Delivery to Mouse Embryonic Stem Cells by Microfluidic Assembled Nanocomplexes
Chee Guan Koh1, Xihai Kang2, Yubing Xie2, Bo Yu1 and L. James Lee3, (1)Department of Chemical and Biomolecular Engineering, The Ohio State University, 140 West 19th Avenue, Columbus, OH 43210, (2)NSEC Center for Affordable Nanoengineering of Polymer Biomedical Devices, The Ohio State University, 1381 Kinnear Road, Suite 100, Columbus, OH 43212, (3)Chemical and Biomolecular Engineering, The Ohio State University, 125A Koffolt, 140 West 19th, Columbus, OH 43210 |
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