Preliminary Program subject to change
15E04 Stem Cells in Tissue Engineering
OverviewStem cells with their ability to self-renew extensively and their capacity for multilineage differentiation are an ideal, inexhaustible source of tissue for clinical applications. This session will focus on bioengineering approaches aiming at furthering our knowledge in the field of stem/progenitor cell biology and developing systems that will facilitate the realization of stem/progenitor cell-based biomedical and biotechnology applications. Topics of interest include, but are not limited to: maintenance of stem cell self-renewal, directed functional differentiation of stem/progenitor cells, studies on stem cell-derived tissue development and morphogenesis, expansion and/or differentiation of stem/progenitor cells using tissue engineering scaffolds and scalable bioreactors.
Primary SponsorEngineering Fundamentals in Life Science (15e)

Chair

E. Manolis Tzanakakis
Assistant Professor
Department of Chemical and Biological Engineering
State University of New York at Buffalo
907 Furnas Hall
Buffalo, NY 14260
Phone Number: 716-645-2911
Fax Number: 716-645-3822
Email: emtzan@eng.buffalo.edu

CoChair

Milica Radisic
Assistan Professor
IBBME/Chemical Engineering and Applied Chemistry
University of Toronto
200 College St. Rm. 368
Toronto, ON M5S 3E5
Canada
Phone Number: 416-978-3063
Email: milica@chem-eng.utoronto.ca
Culture Under Low Oxygen Conditions Markedly Enhances Differentiation Of Murine Embryonic Stem Cells Into Cardiomyocytes
Jeffrey R. Millman1, Daryl E. Powers2, Joao Paulo M. Mattos Almeida1 and Clark K. Colton2, (1)Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave., Room 66-457, Cambridge, MA 02139, (2)Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave., Room 66-452, Cambridge, MA 02139
In Vitro Model System for Cardiac Stem Cell Therapy
Jana Dengler1, Peter Zandstra1 and Milica Radisic2, (1)University of Toronto, Toronto, ON M5S 3G9, Canada, (2)IBBME/Chemical Engineering and Applied Chemistry, University of Toronto, 164 College Street, Room 407, Toronto, ON M5S 3G9, Canada
Electrophysiological Characterization of Embryonic Stem Cell Derived Cardiomyocytes for Use in Cardiac Tissue Engineering
Elizabeth A. Lipke1, Nicolas Christoforou2, Worawan Limpitikul1, John Gearhart2 and Leslie Tung1, (1)Department of Biomedical Engineering, Johns Hopkins University, Traylor Rm #703, 720 Rutland Ave., Baltimore, MD 21205, (2)Johns Hopkins University, Traylor Rm #703, 720 Rutland Ave., Baltimore, MD 21205
Retinoic Acid And Bmp Signaling Synergize To Efficiently Direct Human Embryonic Stem Cells To The Keratinocyte Lineage
Christian M. Metallo, Lin Ji, Juan J. De Pablo and Sean P. Palecek, Chemical and Biological Engineering, University of Wisconsin-Madison, 1415 Engineering Drive, Madison, WI 53706
Break
Directed Differentiation Of Embryonic Stem Cells Towards Insulin-Producing Pancreatic Cells
Ipsita Banerjee, Massachusetts General Hospital, Harvard Medical School, 51 Blossom Street, Boston, MA 02114, Natesh Parashurama, Department of Chemical Engineering, Rutgers, The State University of New Jersey, Massachusetts General Hospital, Harvard Medical School, 51 Blossom St, Boston, MA 02114, Arno Tilles, Massachusetts General Hospital, Harvard Medical School, 51 Blossom street, Boston, MA 02114 and Martin Yarmush, Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medial School, 51 Blossom Street, Boston, MA 02114
Rational Design of in Vitro Hematopoietic Stem Cell Niches: Identifying Cellular Gradients within the Bone Marrow Microenvironment
Brendan A. Harley1, John E. Mahoney2, Shin-Young Park3, Yi Le3, Alexei Protopopov2 and Leslie E. Silberstein3, (1)Children's Hospital, Karp Family Research Building, 10th Floor, Room 10004B, 1 Blackfan Circle, Boston, MA 02115, (2)Dana-Farber Cancer Institute, Boston, MA 02115, (3)Children's Hospital, Karp Family Research Building, 10th Floor, Room 10217, 1 Blackfan Circle, Boston, MA 02115
Osteogenic Potential Of Cells From The Wharton's Jelly Of Human Umbilical Cords Cultured In 2D And 3D Environments
Jose F. Alvarez-Barreto1, Emily Burdett1, Hope Baumgarner1, Rita Abousleiman2 and Vassilios I. Sikavitsas1, (1)Chemical, Biological and Materials Engineering, University of Oklahoma, 100 E. Boyd St. Rm T-335, Norman, OK 73019, (2)Bioengineering Center, University of Oklahoma, 100 E Boyd, T-335, Norman, OK 73019

Food, Pharmaceutical & Bioengineering Division