Activating Innate Immunity Through Toll-Like Receptors: Mechanism Of Signal Induction Is Elucidated By Quantifying Receptor-Ligand Complex Formation
Joshua N. Leonard1, Janine Askins1, Yan Wang1, Rodolfo Ghirlando2, Joseph Shiloach3, Jessica K. Bell4, David H. Margulies5, David R. Davies2 and David M. Segal1, (1)Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, 9000 Rockville Pike, Bldg. 10 Rm. 4B36, Bethesda, MD 20892, (2)Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, (3)Biotechnology Unit (OD), National Institute of Diabetes, Digestive, and Kidney Diseases, 9000 Rockville Pike, Building 14A/Room 176, Bethesda, MD 20892, (4)Department of Biochemistry, Virginia Commonwealth University, Richmond, WA 23298, (5)Molecular Biology Section, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 |
Novel Flow Patterns Reveal A Localized Mechanoreceptor Of Fluid Shear Stress In Endothelial Cells
Cynthia Reinhart-King, Department of Biomedical Engineering, Cornell University, Ithaca, NY 14642 and Keigi Fujiwara, Cardiovascular Reserach Institute, University of Rochester, Rochester, NY 14642 |
Improved Statistical Approach To Quantification Of Tether Bond Dynamics
Ian J. Laurenzi, Chemical Engineering, Lehigh University, B330 Iacocca Hall, 111 Research Dr., Bethlehem, PA 18015 |
Direct and Indirect Regulation of Growth Factor Binding and Signaling by Proteoglycan Binding Competitors
Kimberly Forsten-Williams1, Chia Lin Chu2, Jo Ann Buczek-Thomas2 and Matthew A. Nugent2, (1)Dept. of Chemical Engineering, Virginia Tech, Blacksburg, VA 24061, (2)Dept. of Biochemistry, Boston University School of Medicine, Boston, MA |
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Use Of Trail To Deliver An Apoptotic Signal To Rolling Cancer Cells Under Shear
Kuldeepsinh Rana, Department of Chemical Engineering, University of Rochester, 206 Gavett Hall, RC Box 270166, Rochester, NY 14627, Nichola Charles, Department of Biomedical Engineering, University of Rochester, 601 Elmwood Ave, Rochester, NY 14642, Jane L. Liesveld, Leukemia/Blood and Marrow Transplant Program, James P. Wilmot Cancer Center, University of Rochester, 601 Elmwood Ave, Rochester, NY 14642 and Michael R. King, University of Rochester, Department of Chemical Engineering, 311A Towne Bldg., 220 South 33rd Street, Rochester, NY 14642 |
Signaling Crosstalk Between Soluble Factors And Cell-Cell Interactions
Nicholas A. Graham1, Jin-Hong Kim2, Melissa Pope2 and Anand R. Asthagiri3, (1)California Institute of Technology, 1200 E. California Blvd, MC 210-41, Pasadena, CA 91125, (2)Division of Engineering & Applied Science, California Institute of Technology, 1200 E. California Blvd, MC 210-41, Pasadena, CA 91125, (3)Chemical Engineering, California Institute of Technology, 1200 E. California Blvd MC 210-41, Pasadena, CA 91125 |
Identifying Downstream Targets Of Cox-2 Which Regulate Extracellular Matrix Maintenance And Apoptosis In Shear-Induced Chondrocytic Cells
Joshua David Stull, Zachary Ryan Healy and Konstantinos Konstantopoulos, Chemical and Biomolecular Engineering, Johns Hopkins University, 3400 N. Charles Street, Maryland Hall Rm 223, Baltimore, MD 21218 |
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