Optimization of Primary and Secondary Clarification Using Failure Mode and Effect Analysis
Kara Fothergill, Bioprocess Division, Millipore Corporation, 900 Middlesex Turnpike, Billerica, MA 01821 and Willem Kools, Millipore Corporation, 900 Middlesex Turnpike, Billerica, MA 01821 |
Characterization Of Downstream Processing Steps Used In The Purification Of A Monoclonal Antibody
Nihal Tugcu1, Jonida Basha1, M. Ellen Dahlgren2, David J. Roush2 and Kent E. Goklen2, (1)BioPurification Development, Merck and Co., Inc., RY805S-100, 126 E. Lincoln Ave. PO Box 2000, Rahway, NJ 07065, (2)BioPurification Development, Merck & Co., 126 E. Lincoln Ave., P.O. Box 2000, Rahway, NJ 07065 |
Application Of Process Analytical Technology Towards A Chromatography Step In A Biotech Process
Marcella Yu1, Samuel Yeboah2, Ashutosh Sharma2 and Anurag Rathore2, (1)Chemical and Biomolecular Engineering Department, University of California, Los Angeles, 5531 Boelter Hall, 420 Westwood Plaza, Los Angeles, CA 90095, (2)Process Development, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320 |
Modeling Of Vapor-Liquid Equilibrium To Design A Rectifying Column For The Isolation Of An Active Pharmaceutical Ingredient Intermediate From A Biotransformation Reaction
Mark Brower1, Kent E. Göklen1 and Brendan Grau2, (1)BioPurification Development, Merck & Co. Inc., 126 E. Lincoln Ave., P.O. Box 2000, Rahway, NJ 07065, (2)Process Research, Merck & Co. Inc., 126 E. Lincoln Ave., P.O. Box 2000, Rahway, NJ 07065 |
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Efficient Influenza Virus Capture From Cell Cultivation Broth By A Novel Affinity Chromatography
Lars Opitz1, Anke Zimmermann1, Sylvia Lehmann1, Yvonne Genzel1, Holger Lübben2, Udo Reichl1 and Michael W. Wolff1, (1)Bioprocess Eng., Max Planck Institute, Sandtorstrasse 1, Magdeburg, 39106, Germany, (2)Novartis Behring, Marburg, 35041, Germany |
Scale-up of Constant Pressure Operations
Willem Kools and Jonathan Royce, Millipore Corporation, 900 Middlesex Turnpike, Billerica, MA 01821 |
Characterization Of A Hybrid Particle-Nonwoven Membrane Separation Medium
M. Omon Herigstad, Chemical and Biomolecular Engineering, North Carolina State University, EB1 RM 2098, Box 7905, 911 Partners Way, Raleigh, NC 27695, Patrick V. Gurgel, ProMetic Life Sciences, 8168 Montview Rd, Mont-Royal, QC H4P 2L7, Canada and Ruben Carbonell, Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC 27606 |
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